How far is San Jose from Panama City?

The distance separating San Jose and Panama City is 2124 miles (3425 km).

What are the departure and arrival stations when taking the bus from San Jose to Panama City?

Most of the buses traveling from San Jose to Panama City leave from Diridon Station and arrive at Panama City Greyhound Bus Station. These are the most popular departure and arrival locations on this route, but you can find others that could fit better into your travel plans.

What are the best sights and things to do in Panama City?

Once in Panama City, you can start exploring the city and discover its surroundings. The top sights and things to do are The Biomuseo, Shopping, Panama Rainforest Discovery Center, Ancon Hill and Casco Antiguo.

Bus San Jose to Panama City from $159 | Refundable Tickets

Next departures

Next departures for San Jose to Panama City on November 10
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
FlixBus + Greyhound Lines, Inc.		9:25am	Diridon Station	2d 20h	7:25am	Panama City Beach Station	Cheapest
		12:55am	Diridon Station	2d 18h	9:35pm	Panama City Beach Station	Fastest

Last refresh of the prices: Yesterday at 5:13 AM PST.

Get from San Jose to Panama City

This route is served by bus only

The journey takes about 2 days, 19 hours 55 minutes and with fares starting at just $162, it presents an excellent value for a comfortable ride.

3bus per day

2d 19hAverage Duration

2115 milesDistance

85kgCO₂ emissions

Compare bus companies

Greyhound

3.5/587,357 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/511,215 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Where are the popular stops in San Jose and Panama City?

Stops in San Jose

A - Diridon Station

B - Santiago Express San Jose

C - 1118 E William St

D - San Jose Bus Stop

E - Tamien Station

F - Diridon Station

Stops in Panama City

A - Panama City Greyhound Bus Station

Frequently asked questions about traveling from San Jose, US to Panama City, US by bus

How far is San Jose from Panama City?
What are the departure and arrival stations when taking the bus from San Jose to Panama City?
What are the best sights and things to do in Panama City?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/05

No data

11/06

$227

Today

No data

11/08

$194

11/09

$159

11/10

$276

11/11

$189

11/12

No data

The cheapest trip from San Jose, US to Panama City, US was searched and found on Nov 9, 2025 with a price of $159

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Jose, US to Panama City, US, as early as possible.

You can expect to pay from $159 to $276 for a bus ticket from San Jose, US to Panama City, US based on the last 2 days. You can expect to find the cheapest price for the trip at $159 which is on 2025-11-09.

Top traveled bus routes

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