Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Santander (Estacion de Autobuses) | Prague (Main Station - parking) | No tags | ||||
| Bus | Santander (Estacion de Autobuses) | Prague (Central Bus Station Florenc) | No tags | ||||
| Bus | Santander (Estacion de Autobuses) | Prague (Main Railway Station) | No tags | ||||
| Bus | Santander (Estacion de Autobuses) | Prague (Main Railway Station) | No tags | ||||
| Bus | Santander (Estacion de Autobuses) | Holešovice | No tags |
Get from Santander to Prague
The journey takes about 1 day, 12 hours 50 minutes, and with fares starting at just R 1 939, it presents an excellent value for a comfortable ride.
Where are the popular stops in Santander and Prague?
Stops in Santander
- ACalle Navas de Tolosa, 2, 39002 Santander, Cantabria, Spain
- B
Santander Airport
- C
Av. de los Castros 43A
Av. de los Castros 43A, 39005 Santander, Cantabria, Spain - D
Calle Camarreal-Ojaiz
Calle Camarreal-Ojaiz, 52, 39011 Santander, Cantabria, Spain - E
Av. de Pontejos
Av. de Pontejos, 33A, 39005 Santander, Cantabria, Spain - F
Estación Marítima
39002 Santander, Cantabria, Spain
Stops in Prague
- A
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic - BTomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
- CAviatická, 161 08, Praha 6, Czechia
- DKřižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
- EChlumecká, 198 00 Praha 20, Czech Republic
- F300/8 Wilsonova, 110 00 Praha, Czechia
Compare bus companies
Based on 11974 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. FlixBus ticket prices on this trip start at R 1 939
Frequently asked questions about travelling from Santander to Prague by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Santander to Prague?
The cheapest bus tickets from Santander to Prague start at R 1 939. The average price for this route is around R 2 153. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Santander to Prague?
The average bus journey time from Santander to Prague is 1d 12h, covering a distance of 1568 km. The fastest bus gets you there in 1d 12h and is operated by FlixBus.
Which bus companies service the Santander to Prague route?
Several major bus companies operate on this route with 6 buses available per day.
What is the earliest and latest departure time for the bus from Santander to Prague?
The earliest bus departs from Santander to Prague at 18:50. And the latest bus departs at 18:50.
What are the CO₂ emissions for the bus trip from Santander to Prague?
A bus trip from Santander to Prague produces an estimated 39 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santander to Prague was searched and found on 14 Jan 2026 with a price of R 1 875To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santander to Prague as early as possible.
You can expect to pay from R 1 875 to R 2 151 for a bus ticket from Santander to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 875, which is on 2026-01-14.
