Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Santarem | Brussels-South (Gare du Midi) | No tags | ||||
| Bus | Santarem | Brussels-South (Gare du Midi) | No tags | ||||
| Bus | Santarem | Brussels-South (Gare du Midi) | No tags | ||||
| Bus | Santarem | Brussels-South (Gare du Midi) | No tags | ||||
| Bus | Santarem | Brussels-South (Gare du Midi) | No tags |
Get from Santarem to Brussels
The journey takes about 1 day, 8 hours 40 minutes, and with fares starting at just R 1 546, it presents an excellent value for a comfortable ride.
Where are the popular stops in Santarem and Brussels?
Stops in Santarem
- AAv. do Brasil 39, 2005-155 Santarém, Portugal
Stops in Brussels
- ARue de France 85, 1060 Saint-Gilles, Belgium
- BBoulevard Simon Bolivar 7, 1030 Schaerbeek, Belgium
- CPachecolaan 5, 1000 Brussel, Belgium
- D
Centrale
Rue de Loxum 5, 1000 Bruxelles, Belgium
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Frequently asked questions about travelling from Santarem to Brussels by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Santarem to Brussels?
The cheapest bus tickets from Santarem to Brussels start at R 1 546. The average price for this route is around R 2 020. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Santarem to Brussels?
The average bus journey time from Santarem to Brussels is 1d 8h, covering a distance of 1647 km. The fastest bus gets you there in 1d 5h and is operated by BlaBlaCar Bus.
Which bus companies service the Santarem to Brussels route?
Several major bus companies operate on this route with 5 buses available per day, including services from FlixBus, BlaBlaCar Bus.
What is the earliest and latest departure time for the bus from Santarem to Brussels?
The earliest bus departs from Santarem to Brussels at 07:05. And the latest bus departs at 20:00.
What are the CO₂ emissions for the bus trip from Santarem to Brussels?
A bus trip from Santarem to Brussels produces an estimated 41 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Santarem to Brussels?
According to Busbud customers, the highest-rated bus company on this route is BlaBlaCar Bus, with an average rating of 3.7 out of 5 stars based on 11197 reviews.
Which bus company has the best Wi-Fi from Santarem to Brussels?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Santarem to Brussels?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Santarem to Brussels?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is BlaBlaCar Bus, with a cleanliness rating of 4.3 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santarem to Brussels was searched and found on 17 Dec 2025 with a price of R 1 481To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santarem to Brussels as early as possible.
You can expect to pay from R 1 481 to R 1 481 for a bus ticket from Santarem to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 481, which is on 2025-12-17.
