Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Santarem | Brussels-South (Gare du Midi) | No tags | ||||
| Bus | Santarem | Brussels-South (Gare du Midi) | No tags | ||||
| Bus | Santarem | Brussels-South (Gare du Midi) | No tags | ||||
| Bus | Santarem | Brussels-South (Gare du Midi) | No tags | ||||
| Bus | Santarem | Brussels-South (Gare du Midi) | No tags |
Get from Santarem to Brussels
The journey takes about 1 day, 8 hours 40 minutes, and with fares starting at just $127, it presents an excellent value for a comfortable ride.
Where are the popular stops in Santarem and Brussels?
Stops in Santarem
- AAv. do Brasil 39, 2005-155 Santarém, Portugal
Stops in Brussels
- ARue de France 85, 1060 Saint-Gilles, Belgium
- BBoulevard Simon Bolivar 7, 1030 Schaerbeek, Belgium
- CPachecolaan 5, 1000 Brussel, Belgium
- D
Centrale
Rue de Loxum 5, 1000 Bruxelles, Belgium
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Frequently asked questions about travelling from Santarem to Brussels by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Santarem to Brussels?
The cheapest bus tickets from Santarem to Brussels start from $127. The average price for this route is around $165. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Santarem to Brussels?
The average bus travel time from Santarem to Brussels is 1d 8h, covering a distance of 1647 km. The quickest bus can get you there in 1d 5h and is operated by BlaBlaCar Bus.
Which bus companies service the Santarem to Brussels route?
Several major bus companies operate on this route with 5 buses available per day, including services from FlixBus, BlaBlaCar Bus.
What are the earliest and latest departure times for the bus from Santarem to Brussels?
The earliest bus departs from Santarem to Brussels at 7:05am. And the latest bus departs at 8:00pm.
What are the CO₂ emissions for the bus trip from Santarem to Brussels?
A bus trip from Santarem to Brussels generates an estimated 41 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Santarem to Brussels?
According to Busbud customers, the highest-rated bus company on this route is BlaBlaCar Bus, with an average rating of 3.7 out of 5 stars based on 11197 reviews.
Which bus company has the best Wi-Fi from Santarem to Brussels?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Santarem to Brussels?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Santarem to Brussels?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is BlaBlaCar Bus, with a cleanliness rating of 4.3 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santarem to Brussels was searched and found on Dec 17, 2025 with a price of $121To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santarem to Brussels, as early as possible.
You can expect to pay from $121 to $121 for a bus ticket from Santarem to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at $121 which is on 2025-12-17.
