Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Newark (DE) | Niagara Frontier Transportation Authority | Cheapest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Wilmington Bus Station | Niagara Frontier Transportation Authority | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Wilmington Bus Station | Niagara Frontier Transportation Authority | No tags | ||||
 | Bus | Wilmington Bus Station | Niagara Frontier Transportation Authority | No tags | ||||
| Bus | Newark (DE) | Niagara Frontier Transportation Authority | No tags |
Last refresh of the prices: Today at 6:18 PM EST.
Compare 2 ways to travel from Wilmington to Buffalo
Among the sustainable travel choices, the bus stands out as a good way to reach Buffalo. The journey takes about 15 hours 40 minutes and with fares starting at just R 1 256, it presents an excellent value for a comfortable ride.
Where are the popular stops in Wilmington and Buffalo?
Stops in Wilmington
- AWilmington Bus Station, 101 N French St, Wilmington, DE 19801, USA
- B100 French St, Wilmington, DE 19801, USA
- C
Wilmington Bus Stop
101 N French , Wilmington, DE 19801
Stops in Buffalo
- A
Buffalo Airport
- B185 Ellicott St, Buffalo, NY 14203, USA
- C75 Exchange St, Buffalo, NY 14203, USA
Compare bus companies
Frequently asked questions about travelling from Wilmington, DE to Buffalo, NY by bus
How much does a bus ticket from Wilmington to Buffalo cost?
The bus ticket price from Wilmington to Buffalo starts at R 1 256. The best way to find cheap bus tickets from Wilmington to Buffalo is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Wilmington to Buffalo?
The average travel time between Wilmington and Buffalo is around 15h 40m, although the fastest bus will take about 12h 5m. This is the time it takes to travel the 449 km that separates the two cities.
How many daily bus connections are there between Wilmington and Buffalo?
The number of buses from Wilmington to Buffalo can differ depending on the day of the week. On average, there are 28 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Wilmington to Buffalo by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Wilmington to Buffalo?
When taking the bus from Wilmington to Buffalo, you can travel comfortably and safely with FlixBus, Greyhound.
What are the departure and arrival stations when taking the bus from Wilmington to Buffalo?
Buses travelling between Wilmington and Buffalo leave from Wilmington Bus Station or Wilmington Station and arrive at Buffalo Airport, Transportation Center, Exchange Street Station.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Wilmington, DE to Buffalo, NY was searched and found on 24 Nov 2025 with a price of R 1 509To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Wilmington, DE to Buffalo, NY as early as possible.
You can expect to pay from R 1 509 to R 2 710 for a bus ticket from Wilmington, DE to Buffalo, NY based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 509, which is on 2025-11-24.
What's the cheapest way to go from Wilmington, DE to Buffalo, NY?
The bus is the cheapest travel choice for this destination
