Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Greenville Station | Chicago (Union Station), IL | No tags | ||||
| Train | Greenville Station | Chicago (Union Station), IL | No tags | ||||
| Train | Greenville Station | Chicago (Union Station), IL | No tags | ||||
| Train | Greenville Station | Chicago (Union Station), IL | No tags | ||||
| Train | Greenville Station | Chicago (Union Station), IL | No tags |
Compare 2 ways to travel from Greenville to Chicago
Among the sustainable travel choices, the bus stands out as a good way to reach Chicago. The journey takes about 21 hours 30 minutes and with fares starting at just R 1 723, it presents an excellent value for a comfortable ride.
Train Companies
Based on 5639 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the Wi-Fi. Amtrak ticket prices on this trip start at R 3 045
Frequently asked questions about travelling from Greenville, SC to Chicago by train
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the train ticket from Greenville to Chicago?
The cheapest train tickets from Greenville to Chicago start from R 3 045. The average price for this train route is around R 5 801. Busbud recommends booking your tickets in advance for a better chance to secure the lowest possible price.
How long is the train journey from Greenville to Chicago?
The average train journey time from Greenville to Chicago is 1d 7h, covering a distance of 904 km. The quickest train can get you there in 1d 7h and is operated by Amtrak.
Which train operators serve the Greenville to Chicago route?
Several major train operators run on this route, with 1 trains available per day.
What are the earliest and latest departure times for the train from Greenville to Chicago?
The earliest train from Greenville to Chicago departs at 02:23. And the latest train departs at 02:23.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Greenville, SC to Chicago was searched and found on 17 Dec 2025 with a price of R 3 268To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Greenville, SC to Chicago as early as possible.
You can expect to pay from R 3 268 to R 19 691 for a train ticket from Greenville, SC to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at R 3 268, which is on 2025-12-17.
