Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Via Gandhi | Rome Anagnina | No tags | ||||
| Bus | Via Gandhi | Rome Tiburtina Bus Station | No tags | ||||
| Bus | Via Gandhi | Rome Tiburtina Bus Station | No tags | ||||
| Bus | Via Gandhi | Rome Anagnina | No tags | ||||
| Bus | Via Gandhi | Rome Fiumicino Airport | No tags |
Compare 2 ways to go from Comiso to Rome
Among the sustainable travel choices, the Carpool stands out as the good way to reach Rome. The journey takes about 10 hours 10 minutes and with fares starting at just $60, it presents an excellent value for a comfortable ride.
| Average Price | Average Duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average Price$35 - $181 | Average Duration21h 10m | 14kg CO₂e | ||
Carpool | Average Price$60 - $84 | Average Duration10h 10m | 24kg CO₂e |
Where are the popular stops in Comiso and Rome?
Stops in Rome
- BLargo Guido Mazzoni, 3, 00162 Roma, Italy
- D
Castro Pretorio
Viale Castro Pretorio 76, 00185 Roma, Italy - E
Roma
- F
Anagnina
Via Vincenzo Giudice, 00173 Roma RM, Italy
Compare bus companies
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Comiso to Rome by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Comiso to Rome?
The cheapest bus tickets from Comiso to Rome start from $35. The average price for this route is around $67. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Comiso to Rome?
The average bus trip duration from Comiso to Rome is 21h 10m, covering a distance of 354 miles (571 km). The quickest bus can get you there in 16h 35m and is operated by FlixBus.
Which bus companies service the Comiso to Rome route?
Several major train operators operate on this route with 3 trains available per day.
What is the earliest and latest departure time for the bus from Comiso to Rome?
The earliest bus departs from Comiso to Rome at 2:30pm. And the latest bus departs at 2:30pm.
What are the CO₂ emissions for the bus trip from Comiso to Rome?
A bus trip from Comiso to Rome generates an estimated 14 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Comiso to Rome was searched and found on Jan 17, 2026 with a price of $31To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Comiso to Rome, as early as possible.
You can expect to pay from $31 to $86 for a bus ticket from Comiso to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at $31 which is on 2026-01-17.
What's the cheapest way to go from Comiso to Rome?
The Bus is the cheapest travel choice for this destination
