Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Enschede Central Train Station | Lampugnano bus station | Cheapest | ||||
| Bus | Enschede Central Train Station | Lampugnano bus station | Fastest | ||||
| Bus | Enschede Central Train Station | Lampugnano bus station | No tags | ||||
| Bus | Enschede Central Train Station | Lampugnano bus station | No tags | ||||
| Bus | Enschede Central Train Station | Milan (San Donato M3) | No tags |
Last refresh of the prices: Last Friday at 11:59 AM CET.
Get from Enschede to Milano
The journey takes about 1 day, 6 hours 15 minutes and with fares starting at just $73, it presents an excellent value for a comfortable ride.
Where are the popular stops in Enschede and Milano?
Stops in Enschede
- A
Enschede Central Station
Stationsplein 10, 7511 JD Enschede, Netherlands
Stops in Milano
- AVia Giulio Natta, 228, 20151 Milano, Italy
- CPiazza I Maggio, 1, 20099 Sesto San Giovanni MI, Italy
- EVia Giuseppe Impastato, 27, 20138 Milano, Italy
- F
Molino Dorino
Molino Dorino, 20151 Milano, Italy
Compare bus companies
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Enschede to Milano by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Enschede to Milano?
The cheapest bus tickets from Enschede to Milano start from $73. The average price for this route is around $76. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Enschede to Milano?
The average bus trip duration from Enschede to Milano is 1d 6h, covering a distance of 476 miles (767 km). The quickest bus can get you there in 1d 1h and is operated by FlixBus.
Which bus companies service the Enschede to Milano route?
Several major train operators operate on this route with 3 trains available per day.
What is the earliest and latest departure time for the bus from Enschede to Milano?
The earliest bus departs from Enschede to Milano at 10:15pm. And the latest bus departs at 10:15pm.
What are the CO₂ emissions for the bus trip from Enschede to Milano?
A bus trip from Enschede to Milano generates an estimated 19 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Enschede to Milano was searched and found on Dec 24, 2025 with a price of $128To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Enschede to Milano, as early as possible.
You can expect to pay from $128 to $204 for a bus ticket from Enschede to Milano based on the last 2 days. You can expect to find the cheapest price for the trip at $128 which is on 2025-12-24.
