Last refresh of the prices: Last Friday at 3:27 PM CET.
Compare 2 ways to go from Plzeň to Brno
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as the good way to reach Brno. The journey takes about 4 hours 35 minutes and with fares starting at just $14, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
A-Express offers 1 daily departures, and you can find tickets starting at $27. The quickest ride takes around 257. A-Express offers a cost-effective solution to get you where you need to be.
Based on 149 reviews, the company was rated 4.5 stars on Busbud. Travelers were especially satisfied with the temperature and the seats but often complained with the wifi. Slovak Lines ticket prices on this trip start at $26
Frequently asked questions about traveling from Plzeň to Brno by bus
How far is Plzeň from Brno?
The distance between the two cities is 150 miles (242 km).
What are the departure and arrival stations when taking the bus from Plzeň to Brno?
Most of the buses traveling from Plzeň to Brno leave from Plzeň Autobusová Zastávka and arrive at Hotelu Grand. These are the main departure and arrival locations on this route, but you can also find other options that could better fit your plans.
What are the best sights and things to do in Brno?
Once in Brno, you can start exploring the city and discover its surroundings. The top sights and things to do are Veveří Castle, Villa Tugendhat, 10 - Z, Labyrinth under Zelný trh square and Brno City Museum – Měnínská Brána.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/23
$15
11/24
$24
Today
No data
11/26
No data
11/27
$10
11/28
$14
11/29
$24
11/30
No data
The cheapest trip from Plzeň to Brno was searched and found on Nov 27, 2025 with a price of $10
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Plzeň to Brno, as early as possible.
You can expect to pay from $10 to $38 for a bus ticket from Plzeň to Brno based on the last 2 days. You can expect to find the cheapest price for the trip at $10 which is on 2025-11-27.
Usually A-Express will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Plzeň to Brno?
The bus is the cheapest travel choice for this destination