Next available departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Hotelu Grand | Florenc | Cheapest | |||||
| Hotelu Grand | Florenc | Fastest | |||||
Vlak společnosti Gepard Express | bus station Grand | Vaclav Havel Airport Prague | No tags | |||||
 | Brno [*CZ],,Benešova tř.hotel GRAND, platform 4, Brno | Praha Hlavní nádraží | No tags | |||||
| Hotelu Grand | PRG Airport | No tags | |||||
 | Hotelu Grand | PRG Airport | No tags | |||||
Vlak společnosti Gepard Express | bus station Grand | Vaclav Havel Airport Prague | No tags | |||||
| Hotelu Grand | Florenc | No tags |
Last refresh of the prices: Today at 7:49 AM CEST.
Compare 2 ways to go from Brno to Prague
Among the sustainable travel choices, the Bus stands out as a good way to reach Prague. The journey takes about 2 hours 35 minutes and with fares starting at just ARS 15,374, it presents an excellent value for a comfortable ride.
Bus stations and stops in Brno and Prague
Stops in Brno
- A
Brno Bus Station
Brno Bus Station, ÚAN Zvonařka, 602 00 Brno-střed, Czechia - B
Hotelu Grand
Benešova 603/2, Brno-město, 602 00 Brno-Brno-střed, Czech Republic - C
Hlavní nádraží
Nádražní 418/1, Brno-město, 602 00 Brno-Brno-střed, Czechia - D
ÚAN Zvonařka
Zvonařka 411, Trnitá, 602 00 Brno-Brno-střed, Czech Republic - E
Vídeňská 98
Vídeňská 98, 619 00 Brno-jih, Czechia - F
Ústřední hřbitov
Vídeňská 306/94, Štýřice, 639 00 Brno-Brno-střed, Czechia
Stops in Prague
- A
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic - B
Tomíčkova
Tomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia - C
Florenc
Křižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic - D
PRG Airport
Aviatická, 161 08, Praha 6, Czechia - E
Černý Most
Chlumecká, 198 00 Praha 20, Czech Republic - F
Hlavní nádraží
300/8 Wilsonova, 110 00 Praha, Czechia
Compare companies
Frequently asked questions about traveling from Brno to Prague by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Brno to Prague?
The cheapest bus tickets from Brno to Prague start from ARS 15,374. The average price for this route is around ARS 22,630. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Brno to Prague?
The average bus trip duration from Brno to Prague is 2h 35m, covering a distance of 117 miles (188 km). The quickest bus can get you there in 2h 20m and is operated by FlixBus.
Which bus companies service the Brno to Prague route?
Several major bus companies operate on this route with 64 buses available per day, including services from FlixBus, RegioJet, Slovak Lines, A-Express, IC Bus, Gepard Express, Monobus.
What is the earliest and latest departure time for the bus from Brno to Prague?
The earliest bus departs from Brno to Prague at 1:30am. And the latest bus departs at 11:59pm.
What are the CO₂ emissions for the bus trip from Brno to Prague?
A bus trip from Brno to Prague generates an estimated 4.6861999999999995 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Brno to Prague?
According to Busbud customers, the highest-rated bus company on this route is Slovak Lines, with an average rating of 4.5 out of 5 stars based on 168 reviews.
Which bus company has the best Wi-Fi from Brno to Prague?
Based on reviews on Busbud, the bus company Slovak Lines has the best Wi-Fi rating with a score of 4.2.
Which bus company has the most timely service from Brno to Prague?
According to Busbud traveler reviews, the most timely bus company on this route is IC Bus, with a punctuality rating of 5.0 out of 5 stars.
Which bus company has the cleanest buses from Brno to Prague?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is IC Bus, with a cleanliness rating of 5.0 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Brno to Prague was searched and found on Jul 27, 2026 with a price of ARS 15,021To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Brno to Prague, as early as possible.
You can expect to pay from ARS 15,021 to ARS 55,448 for a bus ticket from Brno to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at ARS 15,021 which is on 2026-07-27.
What's the cheapest way to go from Brno to Prague?
The Bus is the cheapest travel choice for this destination
