Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Rome Tiburtina Bus Station | Via Gandhi | CheapestFastest |
Last refresh of the prices: Today at 2:22 PM CEST.
Get from Rome to Comiso
The journey takes about 14 hours 48 minutes and with fares starting at just CLP 100,331, it presents an excellent value for a comfortable ride.
Bus stations and stops in Rome and Comiso
Stops in Rome
- A
Rome Tiburtina Bus Station
Largo Guido Mazzoni, 3, 00162 Roma, Italy - D
Castro Pretorio
Viale Castro Pretorio 76, 00185 Roma, Italy - E
Roma
- F
Anagnina
Via Vincenzo Giudice, 00173 Roma RM, Italy
Stops in Comiso
- A
Fermata dell'autobus Comiso
Viale della Resistenza, 643, 97013 Comiso RG, Italy
Compare bus companies
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Rome to Comiso by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Rome to Comiso?
The cheapest bus tickets from Rome to Comiso start from CLP 100,331. The average price for this route is around CLP 113,069. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Rome to Comiso?
The average bus trip duration from Rome to Comiso is 14h 48m, covering a distance of 360 miles (580 km). The quickest bus can get you there in 14h 48m and is operated by FlixBus.
Which bus companies service the Rome to Comiso route?
Several major bus companies operate on this route with 1 buses available per day.
What is the earliest and latest departure time for the bus from Rome to Comiso?
The earliest bus departs from Rome to Comiso at 9:00pm. And the latest bus departs at 9:00pm.
What are the CO₂ emissions for the bus trip from Rome to Comiso?
A bus trip from Rome to Comiso generates an estimated 14.4762 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Rome to Comiso was searched and found on Jul 16, 2026 with a price of CLP 117,034To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rome to Comiso, as early as possible.
You can expect to pay from CLP 117,034 to CLP 117,034 for a bus ticket from Rome to Comiso based on the last 2 days. You can expect to find the cheapest price for the trip at CLP 117,034 which is on 2026-07-16.
