Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus
| Santhià | Rome Tiburtina Bus Station | Cheapest | ||||
| Bus
| Santhià | Rome Tiburtina Bus Station | Fastest | ||||
| Bus
| Santhià | Aeroporto Ciampino Airport (CIA) | No tags | ||||
| Bus
| Santhià | Aeroporto Ciampino Airport (CIA) | No tags | ||||
| Bus
| Santhià | Rome Tiburtina Bus Station | No tags | ||||
| Bus
| Santhià | Rome Tiburtina Bus Station | No tags | ||||
| Bus
| Santhià | Rome Anagnina | No tags | ||||
| Bus
| Santhià | Rome Anagnina | No tags |
Last refresh of the prices: Yesterday at 11:24 PM CEST.
Get from Santhià to Rome
The journey takes about 12 hours 15 minutes and with fares starting at just $30, it presents an excellent value for a comfortable ride.
Bus stations and stops in Santhià and Rome
Stops in Rome
- B
Rome Tiburtina Bus Station
Largo Guido Mazzoni, 3, 00162 Roma, Italy - D
Castro Pretorio
Viale Castro Pretorio 76, 00185 Roma, Italy - E
Roma
- F
Anagnina
Via Vincenzo Giudice, 00173 Roma RM, Italy
Compare bus companies
Frequently asked questions about traveling from Santhià to Rome by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Santhià to Rome?
The cheapest bus tickets from Santhià to Rome start from $30. The average price for this route is around $72. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Santhià to Rome?
The average bus trip duration from Santhià to Rome is 12h 15m, covering a distance of 326 miles (525 km). The quickest bus can get you there in 10h 19m and is operated by Itabus.
Which bus companies service the Santhià to Rome route?
What is the earliest and latest departure time for the bus from Santhià to Rome?
The earliest bus departs from Santhià to Rome at 7:20am. And the latest bus departs at 9:25pm.
What are the CO₂ emissions for the bus trip from Santhià to Rome?
A bus trip from Santhià to Rome generates an estimated 13.124675 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Santhià to Rome?
According to Busbud customers, the highest-rated bus company on this route is Itabus, with an average rating of 3.8 out of 5 stars based on 1084 reviews.
Which bus company has the best Wi-Fi from Santhià to Rome?
Based on reviews on Busbud, the bus company Itabus has the best Wi-Fi rating with a score of 2.8.
Which bus company has the most timely service from Santhià to Rome?
According to Busbud traveler reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Santhià to Rome?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santhià to Rome was searched and found on Oct 17, 2026 with a price of $34To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santhià to Rome, as early as possible.
You can expect to pay from $34 to $148 for a bus ticket from Santhià to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at $34 which is on 2026-10-17.
