Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Terminal Interbus | Milan (Malpensa Airport Terminal 1) | Cheapest | ||||
| Bus | Terminal Interbus | Lampugnano bus station | Fastest | ||||
| Bus | Terminal Interbus | Milan (Malpensa Airport Terminal 1) | No tags | ||||
| Bus | Terminal Interbus | Aeroporto Malpensa T2 | No tags | ||||
| Bus | Terminal Interbus | Aeroporto Malpensa T2 | No tags |
Last refresh of the prices: Yesterday at 6:45 AM CEST.
Get from Syracuse to Milano
The journey takes about 1 day, 30 minutes and with fares starting at just $66, it presents an excellent value for a comfortable ride.
Where are the popular stops in Syracuse and Milano?
Stops in Syracuse
- AViale Paolo Orsi, 20, 96100 Siracusa SR, Italy
- B
Siracusa
Piazzale della Stazione Centrale, 21, 96100 Siracusa SR, Italy - C
Siracusa - Terminal Bus (Stazione FS)
Viale Teocrito, 68-74, 96100 Siracusa SR, Italy
Stops in Milano
- APiazza I Maggio, 1, 20099 Sesto San Giovanni MI, Italy
- BVia Giulio Natta, 228, 20151 Milano, Italy
- EVia Giuseppe Impastato, 27, 20138 Milano, Italy
- F
Molino Dorino
Molino Dorino, 20151 Milano, Italy
Compare bus companies
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Syracuse to Milano by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Syracuse to Milano?
The cheapest bus tickets from Syracuse to Milano start from $66. The average price for this route is around $140. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Syracuse to Milano?
The average bus trip duration from Syracuse to Milano is 1d , covering a distance of 666 miles (1074 km). The quickest bus can get you there in 20h 25m and is operated by FlixBus.
Which bus companies service the Syracuse to Milano route?
Several major bus companies operate on this route with 11 buses available per day.
What is the earliest and latest departure time for the bus from Syracuse to Milano?
The earliest bus departs from Syracuse to Milano at 7:15am. And the latest bus departs at 5:20pm.
What are the CO₂ emissions for the bus trip from Syracuse to Milano?
A bus trip from Syracuse to Milano generates an estimated 26.8367 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Syracuse to Milano was searched and found on Jun 2, 2026 with a price of $89To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse to Milano, as early as possible.
You can expect to pay from $89 to $213 for a bus ticket from Syracuse to Milano based on the last 2 days. You can expect to find the cheapest price for the trip at $93 which is on 2026-06-04.
