Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus
| Wuppertal | Prague (Central Bus Station Florenc) | Cheapest | ||||
| Bus
| Wuppertal | Prague (Central Bus Station Florenc) | Fastest | ||||
| Bus
| Wuppertal | Prague (Central Bus Station Florenc) | No tags | ||||
| Bus
| Wuppertal | Prague (Main Station - parking) | No tags | ||||
| Bus
| Wuppertal | Prague (Na Knížecí) | No tags | ||||
| Bus
| Wuppertal | PRG Airport | No tags |
Last refresh of the prices: Yesterday at 5:45 AM CEST.
Compare 2 ways to go from Wuppertal to Prague
Among the sustainable travel choices, the Bus stands out as a good way to reach Prague. The journey takes about 14 hours 35 minutes and with fares starting at just $46, it presents an excellent value for a comfortable ride.
Bus stations and stops in Wuppertal and Prague
Stops in Wuppertal
- A
Wuppertal
Berliner Straße 206, 42277 Wuppertal - B
Wuppertal (Bf. Oberbarmen)
Paul-Humburg-Straße 5-6, 42275 Wuppertal, Germany - C
Döppersberg
Döppersberg 35A, 42103 Wuppertal, Germany
Stops in Prague
- A
Černý Most
Chlumecká, 198 00 Praha 20, Czech Republic - B
PRG Airport
Aviatická, 161 08, Praha 6, Czechia - C
Florenc
Křižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic - D
Tomíčkova
Tomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia - E
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic - F
Hlavní nádraží
300/8 Wilsonova, 110 00 Praha, Czechia
Compare bus companies
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Wuppertal to Prague by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Wuppertal to Prague?
The cheapest bus tickets from Wuppertal to Prague start from $46. The average price for this route is around $73. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Wuppertal to Prague?
The average bus trip duration from Wuppertal to Prague is 14h 35m, covering a distance of 324 miles (522 km). The quickest bus can get you there in 11h 35m and is operated by FlixBus.
Which bus companies service the Wuppertal to Prague route?
Several major bus companies operate on this route with 14 buses available per day.
What is the earliest and latest departure time for the bus from Wuppertal to Prague?
The earliest bus departs from Wuppertal to Prague at 9:55am. And the latest bus departs at 10:40pm.
What are the CO₂ emissions for the bus trip from Wuppertal to Prague?
A bus trip from Wuppertal to Prague generates an estimated 13.048075 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Wuppertal to Prague was searched and found on Sep 25, 2026 with a price of $67To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Wuppertal to Prague, as early as possible.
