How much is the train ticket from Salisbury to St. Louis?

The cheapest train tickets from Salisbury to St. Louis start from $285. The average price for this train route is around $1,108. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the train journey from Salisbury to St. Louis?

The average train ride duration from Salisbury to St. Louis is 1d 13h, covering a distance of 573 miles (923 km). The quickest train can get you there in 1d 13h and is operated by Amtrak .

Which train operators service the Salisbury to St. Louis route?

Several major train operators operate on this route with 1 trains available per day.

What is the earliest and latest departure time for the train from Salisbury to St. Louis?

The earliest train departs from Salisbury to St. Louis at 6:17am. And the latest train departs at 6:17am.

Train Salisbury to St. Louis from $1,154 | Refundable Tickets

Previously seen trips

Next departures for Salisbury to St. Louis on December 12
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	6:17am	Salisbury, NC	1d 13h	7:07pm	Gateway Station	No tags
Train	6:17am	Salisbury, NC	1d 13h	7:07pm	Gateway Station	No tags
Train	6:17am	Salisbury, NC	1d 13h	7:07pm	Gateway Station	No tags
Train	6:17am	Salisbury, NC	1d 13h	7:07pm	Gateway Station	No tags
Train	6:17am	Salisbury, NC	1d 13h	7:07pm	Gateway Station	No tags

Compare 2 ways to go from Salisbury to St. Louis

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach St. Louis. The journey takes about 23 hours 5 minutes and with fares starting at just $124, it presents an excellent value for a comfortable ride.

2bus per day

23h 5mAverage Duration

574 milesDistance

23kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$124 - $326	Average Duration23h 5m	CO₂ emissions 23kg CO₂e
Train	Average Price$285 - $2,303	Average Duration1d 13h	CO₂ emissions 84kg CO₂e

Train Companies

Amtrak

4/55,638 reviews

Staff4.7

Timeliness3.8

Cleanliness4.6

Wifi3.6

Based on 5638 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $285

Train and bus companies in US:Amtrak, Trenitalia, Renfe, VIA Rail Canada, Amtrak Acela, NS Nederlandse Spoorwegen, Iryo

Frequently asked questions about traveling from Salisbury, NC, US to St. Louis by train

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the train ticket from Salisbury to St. Louis?
The cheapest train tickets from Salisbury to St. Louis start from $285. The average price for this train route is around $1,108. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the train journey from Salisbury to St. Louis?
The average train ride duration from Salisbury to St. Louis is 1d 13h, covering a distance of 573 miles (923 km). The quickest train can get you there in 1d 13h and is operated by Amtrak.
Which train operators service the Salisbury to St. Louis route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the train from Salisbury to St. Louis?
The earliest train departs from Salisbury to St. Louis at 6:17am. And the latest train departs at 6:17am.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

12/09

No data

12/10

$334

Today

$1,154

12/12

No data

12/13

No data

12/14

No data

12/15

No data

12/16

No data

The cheapest trip from Salisbury, NC, US to St. Louis was searched and found on Dec 10, 2025 with a price of $334

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Salisbury, NC, US to St. Louis, as early as possible.