Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Salisbury (Citgo Fast Stop) | Gateway Station | CheapestFastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Salisbury (Citgo Fast Stop) | Gateway Station | No tags |
Last refresh of the prices: Last Wednesday at 11:07 PM EST.
Compare 2 ways to go from Salisbury to St. Louis
Among the sustainable travel choices, the bus stands out as the good way to reach St. Louis. The journey takes about 23 hours 5 minutes and with fares starting at just $124, it presents an excellent value for a comfortable ride.
Where are the popular stops in Salisbury and St. Louis?
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Salisbury, NC, US to St. Louis by bus
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Salisbury, NC, US to St. Louis was searched and found on Nov 23, 2025 with a price of $166To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Salisbury, NC, US to St. Louis, as early as possible.
What's the cheapest way to go from Salisbury, NC, US to St. Louis?
The bus is the cheapest travel choice for this destination
