Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Amtrak Station | Florence Station | No tags | ||||
| Train | Amtrak Station | Florence Station | No tags | ||||
| Train | Amtrak Station | Florence Station | No tags | ||||
| Train | Amtrak Station | Florence Station | No tags | ||||
| Train | Amtrak Station | Florence Station | No tags |
Compare 2 ways to go from Syracuse to Florence
Among the sustainable travel choices, the bus stands out as the good way to reach Florence. The journey takes about 20 hours 45 minutes and with fares starting at just $92, it presents an excellent value for a comfortable ride.
Train Companies
Based on 5639 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $219
Frequently asked questions about traveling from Syracuse, US to Florence, SC, US by train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the train ticket from Syracuse to Florence?
The cheapest train tickets from Syracuse to Florence start from $219. The average price for this train route is around $270. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the train journey from Syracuse to Florence?
The average train ride duration from Syracuse to Florence is 20h 4m, covering a distance of 642 miles (1035 km). The quickest train can get you there in 20h 4m and is operated by Amtrak.
Which train operators service the Syracuse to Florence route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the train from Syracuse to Florence?
The earliest train departs from Syracuse to Florence at 7:06am. And the latest train departs at 7:06am.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Syracuse, US to Florence, SC, US was searched and found on Dec 16, 2025 with a price of $236To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Syracuse, US to Florence, SC, US, as early as possible.
You can expect to pay from $236 to $746 for a train ticket from Syracuse, US to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $236 which is on 2025-12-16.
