What is the distance between Syracuse and Florence?

The distance between the two cities is 639 miles (1030 km).

What are the departure and arrival stations when taking the bus from Syracuse to Florence?

If you're headed to Florence from Syracuse, chances are that your bus will depart from Regional Transportation Center and arrive at Florence Bus Station. These are the main pick-up and drop-off locations on this route, but you could find others that could be a better fit for your travel plans.

What are the best sights and things to do in Florence?

Once in Florence, you can start exploring the city and discover its surroundings. The top sights and things to do are Basilica Santa Croce, Palazzo Vecchio, Florence Food Walking Tour, Tuscan Wine Tour and Galleria dell’Accademia.

Bus Syracuse to Florence from $92 | Compare & Save up to 60%

Previously seen trips

Next departures for Syracuse to Florence on November 18
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound + FlixBus	Bus	9:25am	Syracuse (Regional Transportation Center)	20h 10m	5:35am	Florence, SC	No tags
Greyhound + FlixBus	Bus	9:00pm	Syracuse (Regional Transportation Center)	1d 8h	5:35am	Florence, SC	No tags
Greyhound + FlixBus	Bus	3:00pm	Syracuse (Regional Transportation Center)	21h 45m	12:45pm	Bus station	No tags
FlixBus + Greyhound	Bus	9:00pm	Syracuse (Regional Transportation Center)	1d 8h	5:45am	Florence, SC	No tags
Greyhound + FlixBus	Bus	9:25am	Syracuse (Regional Transportation Center)	20h 20m	5:45am	Florence, SC	No tags

Compare 2 ways to go from Syracuse to Florence

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Florence. The journey takes about 20 hours 45 minutes and with fares starting at just $92, it presents an excellent value for a comfortable ride.

2bus per day

20h 45mAverage Duration

642 milesDistance

26kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$92 - $299	Average Duration20h 45m	CO₂ emissions 26kg CO₂e
Train	Average Price$219 - $630	Average Duration20h 4m	CO₂ emissions 94kg CO₂e

Where are the popular stops in Syracuse and Florence?

Stops in Syracuse

A - Regional Transportation Center

B - Syracuse Airport

C - Syracuse University

D - Syracuse University - Lyman Hall

E - New York State Fairgrounds

F - Syracuse, NY

Stops in Florence

A - Florence Bus Station

B - TA Travel Center - Florence

Frequently asked questions about traveling from Syracuse, US to Florence, SC, US by bus

What is the distance between Syracuse and Florence?
What are the departure and arrival stations when taking the bus from Syracuse to Florence?
What are the best sights and things to do in Florence?