Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Südseite Hauptbahnhof | Husova, 2713/60 | No tags | |||||
| Südseite Hauptbahnhof | Husova, 2713/60 | No tags | |||||
| Südseite Hauptbahnhof | Husova, 2713/60 | No tags | |||||
| Südseite Hauptbahnhof | Husova, 2713/60 | No tags | |||||
| Südseite Hauptbahnhof | Husova, 2713/60 | No tags |
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Compare 2 ways to go from Karlsruhe to Plzeň
Busbud recommends taking the train from Karlsruhe to PlzeňAmong the sustainable travel choices, the train stands out as a good way to reach Plzeň. The journey takes about 6 hours 47 minutes, and with fares starting at just US$50, it presents an excellent value for a comfortable ride.
Bus Karlsruhe to Plzeň: Trip Overview
Karlsruhe to Plzeň Bus
With Busbud, comparing and booking tickets for a bus from Karlsruhe to Plzeň is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
Bus service from Karlsruhe to Plzeň will be provided by the most trusted bus companies.
From cheap bus tickets to more luxurious buses travelling from Karlsruhe to Plzeň, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Karlsruhe and Plzeň?
Frequently asked questions on the trip Karlsruhe - Plzeň
What is the travel distance from Karlsruhe to Plzeň?
Karlsruhe and Plzeň are 372 km (231 miles) apart.
What are the departure and arrival locations for buses traveling from Karlsruhe to Plzeň?
Buses departing from Südseite Hauptbahnhof in Karlsruhe will take you to Plzeň Autobusová Zastávka in Plzeň.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Karlsruhe to Plzeň was searched and found on Oct 5, 2025 with a price of US$35To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Karlsruhe to Plzeň, as early as possible.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while travelling from Karlsruhe to Plzeň.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Much more than a mere vehicle taking you from Karlsruhe to Plzeň, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Karlsruhe to Plzeň that are otherwise impossible to come by with a plane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Karlsruhe to Plzeň.
Did you know?
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
What's the cheapest way to go from Karlsruhe to Plzeň?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
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Popular Buses Connecting Karlsruhe
Buses Leaving from Karlsruhe
- Bus from Karlsruhe to Kaiserslautern
- Bus Karlsruhe - Regensburg
- Karlsruhe - Paris
- Bus from Karlsruhe to Hamburg
- Bus Karlsruhe - Stuttgart
- Karlsruhe - Paderborn
- Bus from Karlsruhe to Freiburg
- Bus Karlsruhe - Montabaur
- Karlsruhe - Berlin
- Bus from Karlsruhe to Erfurt
- Bus Karlsruhe - Puttgarden
- Karlsruhe - Friedrichshafen
- Bus from Karlsruhe to Jena
- Bus Karlsruhe - Rosenheim
- Karlsruhe - Magdeburg
Buses Going to Karlsruhe
- Bus from Darmstadt to Karlsruhe
- Bus Paderborn - Karlsruhe
- Regensburg - Karlsruhe
- Bus from Mannheim to Karlsruhe
- Bus Magdeburg - Karlsruhe
- Cologne - Karlsruhe
- Bus from Munich to Karlsruhe
- Bus Bremen - Karlsruhe
- Bonn - Karlsruhe
- Bus from Offenburg to Karlsruhe
- Bus Berlin - Karlsruhe
- Stuttgart - Karlsruhe
- Bus from Heidelberg to Karlsruhe
- Bus Memmingen - Karlsruhe
- Saarbrücken - Karlsruhe
Popular Buses Connecting Plzeň
Buses Leaving from Plzeň
- Bus from Plzeň to Liberec
- Bus Plzeň - Olomouc
- Plzeň - Brno
- Bus from Plzeň to Karlovy Vary
- Bus Plzeň - Písek
- Plzeň - Karlsruhe
- Bus from Plzeň to Hradec Králové
- Bus Plzeň - Jihlava
- Plzeň - České Budějovice
- Bus from Plzeň to Chomutov
- Bus Plzeň - Cheb
- Plzeň - Tabor
- Bus from Plzeň to Uherské Hradiště
- Bus Plzeň - Kromeriz
- Plzeň - Český Krumlov
Buses Going to Plzeň
Popular routes in this country
- Bus from Koblenz to Berlin
- Bus Bremen - Osnabrück
- Frankfurt (Oder) - Berlin
- Bus from Bautzen to Dresden
- Bus Leipzig - Dresden
- Leipzig - Berlin
- Bus from Wiesbaden to Regensburg
- Bus Wiesbaden - Berlin
- Leipzig - Dortmund
- Bus from Bremen to Hanover
- Bus Wiesbaden - Dortmund
- Hamburg - Berlin
- Bus from Wiesbaden to Hamburg
- Bus Regensburg - Marktredwitz
- Düsseldorf - Dresden