Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Fermata dell'autobus Manduria | Siena Train Station | Cheapest | ||||
| Bus | Fermata dell'autobus Manduria | Siena Train Station | Fastest | ||||
 | Bus | Fermata dell'autobus Manduria | Siena Train Station | No tags | ||||
| Bus | Fermata dell'autobus Manduria | Viale Toselli (Penny Market) | No tags |
Last refresh of the prices: Today at 8:48 PM CEST.
Get from Manduria to Siena
The journey takes about 11 hours 55 minutes, and with fares starting at just HK$519, it presents an excellent value for a comfortable ride.
Where are the popular stops in Manduria and Siena?
Stops in Siena
- A
Piazza Gramsci
Piazza Antonio Gramsci, 53100 Siena SI, Italy - B
Via Sallustio Bandini, 21
Via Sallustio Bandini, 21, 53100 Siena SI, Italy - C
Via Giuseppe Mazzini, 58
Via Giuseppe Mazzini, 58, 53100 Siena SI, Italy - D
Via Riccardo Lombardi, 42
Via Riccardo Lombardi, 42, 53100 Siena SI, Italy - E
Torre Fiorentina
Torre Fiorentina, 53100 Siena SI, Italy - F
Siena Zona Industriale
Siena FS, 53100 Siena SI, Italy
Compare bus companies
Based on 934 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the staff and the temperature but often complained with the Wi‑Fi. MarinoBus ticket prices on this trip start at HK$519
Frequently asked questions about travelling from Manduria to Siena by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Manduria to Siena?
The cheapest bus tickets from Manduria to Siena start from HK$519. The average price for this route is around HK$591. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Manduria to Siena?
The average bus travel time from Manduria to Siena is 11h 55m, covering a distance of 616 km. The quickest bus can get you there in 11h 55m and is operated by MarinoBus.
Which bus companies service the Manduria to Siena route?
Several major bus companies operate on this route with 2 buses available per day.
What are the earliest and latest departure times for the bus from Manduria to Siena?
The earliest bus departs from Manduria to Siena at 4:55am. And the latest bus departs at 8:10pm.
What are the CO₂ emissions for the bus trip from Manduria to Siena?
A bus trip from Manduria to Siena generates an estimated 15.39555 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Manduria to Siena was searched and found on Jun 26, 2026 with a price of HK$470To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Manduria to Siena, as early as possible.
You can expect to pay from HK$470 to HK$677 for a bus ticket from Manduria to Siena based on the last 2 days. You can expect to find the cheapest price for the trip at HK$630 which is on 2026-06-27.
