Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Durham Station | Greyhound Amtrak Station | No tags | ||||
| Train | Durham Station | Greyhound Amtrak Station | No tags | ||||
| Train | Durham Station | Greyhound Amtrak Station | No tags | ||||
| Train | Durham Station | Greyhound Amtrak Station | No tags | ||||
| Train | Durham Station | Greyhound Amtrak Station | No tags |
Compare 2 ways to go from Durham to Indianapolis
Among the sustainable travel choices, the Bus stands out as a good way to reach Indianapolis. The journey takes about 23 hours 20 minutes, and with fares starting at just $141, it presents an excellent value for a comfortable ride.
Train companies
Based on 5780 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the Wi‑Fi. Amtrak ticket prices on this trip start at $218
Frequently asked questions about travelling from Durham, NC, US to Indianapolis by train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the train ticket from Durham to Indianapolis?
The cheapest train tickets from Durham to Indianapolis start at $218. The average price for this train route is around $249. Busbud recommends booking your tickets in advance to increase your chances of getting the lowest possible price.
How long is the train ride from Durham to Indianapolis?
The average train trip from Durham to Indianapolis takes 1d 9h and covers 762 km. The quickest train gets you there in 1d 9h and is operated by Amtrak.
Which train operators serve the Durham to Indianapolis route?
Several major train operators serve this route, with 1 trains available per day.
What are the earliest and latest departure times for the train from Durham to Indianapolis?
The earliest train from Durham to Indianapolis departs at 7:06pm. The latest train departs at 7:58pm.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Durham, NC, US to Indianapolis was searched and found on Apr 4, 2026 with a price of $209To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Durham, NC, US to Indianapolis, as early as possible.
You can expect to pay from $209 to $1,876 for a train ticket from Durham, NC, US to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at $209 which is on 2026-04-04.
What's the cheapest way to go from Durham, NC, US to Indianapolis?
The Train is the cheapest travel choice for this destinationThe best way to travel between Durham, NC, US and Indianapolis is by train. By choosing the train, you'll get to save some money as you travel to your destination, as ticket prices cost $249 on average. If you're on a budget, you'll find cheap tickets from $218. If you're looking for the fastest way to get to Indianapolis, choose the train, as it will take you from Durham, NC, US to Indianapolis in about 23h 20m —that's the fastest way to get there!
