Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Florence Station | Jacksonville Amtrak Station | No tags | ||||
| Train | Florence Station | Jacksonville Amtrak Station | No tags | ||||
| Train | Florence Station | Jacksonville Amtrak Station | No tags | ||||
| Train | Florence Station | Jacksonville Amtrak Station | No tags | ||||
| Train | Florence Station | Jacksonville Amtrak Station | No tags |
Compare 2 ways to go from Florence to Jacksonville
Among the sustainable travel choices, the bus stands out as a good way to reach Jacksonville. The journey takes about 5 hours 25 minutes, and with fares starting at just $68, it presents an excellent value for a comfortable ride.
Train companies
Based on 5650 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the WiFi. Amtrak ticket prices on this trip start at $81
Amtrak Florence Jacksonville recent customer reviews
Had never been on any train but enjoyed experience very much now my Nana has riding somewhere by amtrack to her bucket list
Kaitlyn F.
Frequently asked questions about travelling from Florence, SC, US to Jacksonville, FL by train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the train ticket from Florence to Jacksonville?
The cheapest train tickets from Florence to Jacksonville start at $81. The average price for this train route is around $134. Busbud recommends booking your tickets in advance to increase your chances of getting the lowest possible price.
How long is the train ride from Florence to Jacksonville?
The average train trip from Florence to Jacksonville takes 6h 6m and covers 465 km. The quickest train gets you there in 6h 6m and is operated by Amtrak.
Which train operators serve the Florence to Jacksonville route?
Several major train operators serve this route, with 2 trains available per day.
What are the earliest and latest departure times for the train from Florence to Jacksonville?
The earliest train from Florence to Jacksonville departs at 3:18am. The latest train departs at 5:57pm.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Florence, SC, US to Jacksonville, FL was searched and found on Dec 15, 2025 with a price of $96To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Florence, SC, US to Jacksonville, FL, as early as possible.
You can expect to pay from $96 to $1,027 for a train ticket from Florence, SC, US to Jacksonville, FL based on the last 2 days. You can expect to find the cheapest price for the trip at $128 which is on 2025-12-19.
