Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Louise M. Slaughter Station | Gateway Station | No tags | ||||
| Train | Louise M. Slaughter Station | Gateway Station | No tags | ||||
| Train | Louise M. Slaughter Station | Gateway Station | No tags | ||||
| Train | Louise M. Slaughter Station | Gateway Station | No tags | ||||
| Train | Louise M. Slaughter Station | Gateway Station | No tags |
Compare 2 ways to go from Rochester to St. Louis
Among the sustainable travel choices, the train stands out as a good way to reach St. Louis. The journey takes about 20 hours 56 minutes, and with fares starting at just $166, it presents an excellent value for a comfortable ride.
Train companies
Based on 5666 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the WiFi. Amtrak ticket prices on this trip start at $166
Frequently asked questions about travelling from Rochester, NY, US to St. Louis by train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the train ticket from Rochester to St. Louis?
The cheapest train tickets from Rochester to St. Louis start at $166. The average price for this train route is around $335. Busbud recommends booking your tickets in advance to increase your chances of getting the lowest possible price.
How long is the train ride from Rochester to St. Louis?
The average train trip from Rochester to St. Louis takes 20h 56m and covers 1172 km. The quickest train gets you there in 20h 38m and is operated by Amtrak.
Which train operators serve the Rochester to St. Louis route?
Several major train operators serve this route, with 1 trains available per day.
What are the earliest and latest departure times for the train from Rochester to St. Louis?
The earliest train from Rochester to St. Louis departs at 11:29pm. The latest train departs at 11:29pm.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Rochester, NY, US to St. Louis was searched and found on Dec 20, 2025 with a price of $398To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Rochester, NY, US to St. Louis, as early as possible.
You can expect to pay from $398 to $2,943 for a train ticket from Rochester, NY, US to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $398 which is on 2025-12-25.
