Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Rochester | Gateway Station | No tags | ||||
| Bus | Rochester | Gateway Station | No tags | ||||
Greyhound + FlixBus | Bus | Rochester | Gateway Station | No tags | ||||
FlixBus + Greyhound | Bus | Rochester | Gateway Station | No tags | ||||
| Bus | Rochester | Gateway Station | No tags |
Compare 2 ways to go from Rochester to St. Louis
Among the sustainable travel choices, the Train stands out as a good way to reach St. Louis. The journey takes about 1 day, 40 minutes, and with fares starting at just $119, it presents an excellent value for a comfortable ride.
Where are the popular stops in Rochester and St. Louis?
Stops in Rochester
- A186 Cumberland St (Across from the Amtrak Terminal) , Rochester, NY 14605
- BRush Rhees Library, 755 Library Road, Rochester, NY 14627
- C
Rochester Institute of Technology
61 Lomb Memorial Dr, Rochester, NY 14623
Compare bus companies
Frequently asked questions about travelling from Rochester, NY, US to St. Louis by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Rochester to St. Louis?
The cheapest bus tickets from Rochester to St. Louis start from $158. The average price for this route is around $198. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Rochester to St. Louis?
The average bus travel time from Rochester to St. Louis is 1d 5h, covering a distance of 1172 km. The quickest bus can get you there in 1d 4h and is operated by FlixBus.
Which bus companies service the Rochester to St. Louis route?
What are the earliest and latest departure times for the bus from Rochester to St. Louis?
The earliest bus departs from Rochester to St. Louis at 5:10am. And the latest bus departs at 11:35pm.
What are the CO₂ emissions for the bus trip from Rochester to St. Louis?
A bus trip from Rochester to St. Louis generates an estimated 29 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Rochester to St. Louis?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87463 reviews.
Which bus company has the best Wi-Fi from Rochester to St. Louis?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Rochester to St. Louis?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Rochester to St. Louis?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Rochester, NY, US to St. Louis was searched and found on Jan 11, 2026 with a price of $187To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rochester, NY, US to St. Louis, as early as possible.
You can expect to pay from $187 to $401 for a bus ticket from Rochester, NY, US to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $187 which is on 2026-01-11.
What's the cheapest way to go from Rochester, NY, US to St. Louis?
The Bus is the cheapest travel choice for this destination
