Next train departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Waterloo Station | Gateway Station | CheapestFastest | ||||
| Train | Waterloo Station | Gateway Station | No tags | ||||
| Train | Waterloo Station | Gateway Station | No tags | ||||
| Train | Waterloo Station | Gateway Station | No tags | ||||
| Train | Waterloo Station | Gateway Station | No tags |
Last refresh of the prices: Yesterday at 8:12 PM EST.
Get from Waterloo to St. Louis
The journey takes about 16 hours 47 minutes, and with fares starting at just $99, it presents an excellent value for a comfortable ride.
Where are the popular train stations and stops in Waterloo, IN, US and St. Louis?
Train companies
Based on 5652 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the WiFi. Amtrak ticket prices on this trip start at $99
Frequently asked questions about travelling from Waterloo, IN, US to St. Louis by train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the train ticket from Waterloo to St. Louis?
The cheapest train tickets from Waterloo to St. Louis start at $99. The average price for this train route is around $182. Busbud recommends booking your tickets in advance to increase your chances of getting the lowest possible price.
How long is the train ride from Waterloo to St. Louis?
The average train trip from Waterloo to St. Louis takes 16h 47m and covers 541 km. The quickest train gets you there in 12h 16m and is operated by Amtrak.
Which train operators serve the Waterloo to St. Louis route?
Several major train operators serve this route, with 4 trains available per day.
What are the earliest and latest departure times for the train from Waterloo to St. Louis?
The earliest train from Waterloo to St. Louis departs at 6:36am. The latest train departs at 7:51am.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Waterloo, IN, US to St. Louis was searched and found on Dec 17, 2025 with a price of $78To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Waterloo, IN, US to St. Louis, as early as possible.
You can expect to pay from $78 to $988 for a train ticket from Waterloo, IN, US to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $145 which is on 2025-12-22.
