Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Flixbus + Flixtrain | Prague (Central Bus Station Florenc) | Karlsruhe Hbf | Cheapest | |||||
Flixbus + Flixtrain | Prague (Na Knížecí) | Karlsruhe Hbf | Fastest | |||||
Flixbus + Flixtrain | Prague (Na Knížecí) | Karlsruhe Hbf | No tags | |||||
EuroCity Train + Deutsche Bahn ICE | Hlavní nádraží | Karlsruhe Hbf | No tags | |||||
 | Hlavní nádraží | Karlsruhe Hbf | No tags |
Accepted payments
Compare 3 ways to go from Prague to Karlsruhe
| Average Price | Average Duration | CO₂ emissions | |||
|---|---|---|---|---|---|
| Average PriceUS$29 - US$108 | Average Duration10h 20m | 11kg CO₂e5 out of 5 stars | Most eco-friendly | ||
| Average PriceUS$36 - US$200 | Average Duration8h 26m | 11kg CO₂e5 out of 5 stars | |||
Carpool | Average PriceUS$27 - US$36 | Average Duration5h 30m | 19kg CO₂e4 out of 5 stars | CheapestFastest |
Busbud recommends carpooling from Prague to KarlsruheAmong the sustainable travel choices, the carpool stands out as a good way to reach Karlsruhe. The journey takes about 5 hours 30 minutes, and with fares starting at just US$27, it presents an excellent value for a comfortable ride.
Train Prague to Karlsruhe: Trip Overview
Please note, this information is subject to change
Train companies
Based on 1 reviews, the company was rated 5 stars on Busbud. Travellers were especially satisfied with the staff and the timeliness but often complained with the ticket access. Deutsche Bahn EuroCity ticket prices on this trip start at US$38
Prague to Karlsruhe Train
With Busbud, comparing and booking tickets for a train from Prague to Karlsruhe is a breeze. Browse through an extensive selection of train fares and train schedules to find the best deals.
Train service from Prague to Karlsruhe will be provided by the most trusted companies.
Whether it is train tickets or first class train tickets going to Karlsruhe from Prague, we help you find what you're looking for based on how much of a budget you have.
Where are the popular train stations and stops in Prague and Karlsruhe?
Frequently asked questions on the trip Prague - Karlsruhe
How much does a cheap train ticket from Prague to Karlsruhe cost?
The average train ticket price from Prague to Karlsruhe is US$69. The best way to find cheap train tickets from Prague to Karlsruhe is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the trip from Prague to Karlsruhe?
A train trip between Prague and Karlsruhe is around 8h 26m, although the fastest train will take about 8h 6m. This is the time it takes to travel the 453 km that separates the two cities.
How many daily trains are there between Prague and Karlsruhe?
The number of trains from Prague to Karlsruhe can differ depending on the day of the week. On average, there are 7. Some trains are direct while others include transferring trains. Simplify your train trip from Prague to Karlsruhe by comparing and selecting the train that fits your travel style and budget on Busbud.
Which train companies travel from Prague to Karlsruhe?
When taking the train from Prague to Karlsruhe, you can travel comfortably and safely with Deutsche Bahn EuroCity.
What are the departure and arrival stations for a train from Prague to Karlsruhe?
Trains travelling between Prague and Karlsruhe leave from Hlavní nádraží or Florenc and arrive at Karlsruhe Hbf, Südseite Hauptbahnhof.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Prague to Karlsruhe was searched and found on Aug 26, 2025 with a price of US$37To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Prague to Karlsruhe, as early as possible.
You can expect to pay from US$37 to US$240 for a train ticket from Prague to Karlsruhe based on the last 2 days. You can expect to find the cheapest price for the trip at US$42 which is on 2025-08-30.
About Train Travel
Train Travel Tips
Taking the fastest trains allows you to travel at speeds greater than 300 km/h. Taking a trip from Prague to Karlsruhe is not only much quicker but more comfortable too! You can usually travel directly to the city centre and save time while you're at it.
No matter if you plan to take a regional or high-speed train to Karlsruhe, the planet will thank you. You’ll help to protect the beautiful landscapes that will unfold before your very eyes.
By choosing the train between Prague and Karlsruhe, you emit up to 30 times less CO2 than for the same journey made by plane or car!
Make a music playlist for your train ride from Prague to Karlsruhe, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
New York holds the record for the most platforms and track numbers in a single station. Grand Central Station in Manhattan is one of the largest rail terminals in the world with more than 44 platforms and 67 tracks to accommodate passengers.
You can find dogs as passengers on the trains of Moscow, where there is a large number of stray dogs. Over time, the dogs have learned the inner workings of the rail system and it is not uncommon to find one travelling between the city and the suburbs.
The first high-speed train line was inaugurated in 1964, in Japan, to connect Tokyo with Osaka. It was during the Olympics that the first passengers travelled aboard the Shinkansen at a speed of 210 km / h.
Top Travelled Train Routes
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