Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | PRG Airport | Südseite Hauptbahnhof | CheapestFastest | ||||
| Bus | Prague (Central Bus Station Florenc) | Südseite Hauptbahnhof | No tags | ||||
| Bus | Prague (Central Bus Station Florenc) | Südseite Hauptbahnhof | No tags | ||||
| Bus | Prague (Central Bus Station Florenc) | Südseite Hauptbahnhof | No tags | ||||
| Bus | Prague (Central Bus Station Florenc) | Südseite Hauptbahnhof | No tags |
Last refresh of the prices: Today at 12:05 PM CET.
Compare 3 ways to go from Prague to Karlsruhe
Among the sustainable travel choices, the Carpool stands out as a good way to reach Karlsruhe. The journey takes about 5 hours 20 minutes, and with fares starting at just $48, it presents an excellent value for a comfortable ride.
Where are the popular stops in Prague and Karlsruhe?
Stops in Prague
- AChlumecká, 198 00 Praha 20, Czech Republic
- BKřižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
- C
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic - DAviatická, 161 08, Praha 6, Czechia
- ETomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
- F300/8 Wilsonova, 110 00 Praha, Czechia
Stops in Karlsruhe
- AHinterm Hauptbahnhof 6, 76137 Karlsruhe, Germany
- BBahnhofpl. 1A, 76137 Karlsruhe, Germany
- CGoethestraße 17-19, 76135 Karlsruhe, Germany
- D
Karlsruhe
Gartenstraße 58, 76135 Karlsruhe, Germany - E
Karlsruhe/Baden-Baden Airport
Quebec Avenue, 77836 Rheinmünster, Germany
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Frequently asked questions about travelling from Prague to Karlsruhe by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Prague to Karlsruhe?
The cheapest bus tickets from Prague to Karlsruhe start from $43. The average price for this route is around $76. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Prague to Karlsruhe?
The average bus travel time from Prague to Karlsruhe is 10h 25m, covering a distance of 441 km. The quickest bus can get you there in 7h 50m and is operated by FlixBus.
Which bus companies service the Prague to Karlsruhe route?
Several major bus companies operate on this route with 12 buses available per day, including services from FlixBus, BlaBlaCar Bus, LEX CLUB.
What are the earliest and latest departure times for the bus from Prague to Karlsruhe?
The earliest bus departs from Prague to Karlsruhe at 2:30am. And the latest bus departs at 11:50pm.
What are the CO₂ emissions for the bus trip from Prague to Karlsruhe?
A bus trip from Prague to Karlsruhe generates an estimated 11 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Prague to Karlsruhe?
According to Busbud customers, the highest-rated bus company on this route is BlaBlaCar Bus, with an average rating of 3.7 out of 5 stars based on 11385 reviews.
Which bus company has the best Wi-Fi from Prague to Karlsruhe?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Prague to Karlsruhe?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Prague to Karlsruhe?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is BlaBlaCar Bus, with a cleanliness rating of 4.3 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Prague to Karlsruhe was searched and found on Jan 26, 2026 with a price of $55To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Karlsruhe, as early as possible.
You can expect to pay from $55 to $85 for a bus ticket from Prague to Karlsruhe based on the last 2 days. You can expect to find the cheapest price for the trip at $55 which is on 2026-01-26.
