Next train departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Santander | Madrid-Chamartin | Cheapest | ||||
| Train | Santander | Madrid-Chamartin | Fastest | ||||
| Train | Santander | Madrid-Chamartin | No tags | ||||
| Train | Santander | Madrid-Chamartin | No tags | ||||
| Train | Santander | Madrid-Chamartin | No tags |
Last refresh of the prices: Today at 5:29 PM CET.
Compare 3 ways to go from Santander to Madrid
Among the sustainable travel choices, the carpool stands out as a good way to reach Madrid. The journey takes about 4 hours 20 minutes, and with fares starting at just $29, it presents an excellent value for a comfortable ride.
Where are the popular train stations and stops in Santander and Madrid?
Santander
- ACalle Navas de Tolosa, 2, 39002 Santander, Cantabria, Spain
Madrid
- AC. de la Hiedra, 5, 28036 Madrid, Spain
- BMadrid Atocha railway station, Plaza del Emperador Carlos V, 28045 Madrid, Spain
- CPríncipe Pío, 28008 Madrid, Spain
- E
Nuevos Ministerios
Estación de Nuevos Ministerios, 28046 Madrid, Spain
Train companies
Based on 923 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the staff and the seats but often complained with the WiFi. Renfe ticket prices on this trip start at $47
Frequently asked questions about travelling from Santander to Madrid by train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the train ticket from Santander to Madrid?
The cheapest train tickets from Santander to Madrid start at $47. The average price for this train route is around $77. Busbud recommends booking your tickets in advance to increase your chances of getting the lowest possible price.
How long is the train ride from Santander to Madrid?
The average train trip from Santander to Madrid takes 4h 16m and covers 333 km. The quickest train gets you there in 4h 16m and is operated by Renfe.
Which train operators serve the Santander to Madrid route?
Several major train operators serve this route, with 1 trains available per day.
What are the earliest and latest departure times for the train from Santander to Madrid?
The earliest train from Santander to Madrid departs at 1:58pm. The latest train departs at 7:00pm.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santander to Madrid was searched and found on Dec 3, 2025 with a price of $41To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Santander to Madrid, as early as possible.
You can expect to pay from $41 to $153 for a train ticket from Santander to Madrid based on the last 2 days. You can expect to find the cheapest price for the trip at $61 which is on 2025-12-06.
