Find coaches from Florence, SC, US to Philadelphia, PA

Find affordable coach tickets from Florence, SC, US to Philadelphia, PA with flexible options. Book your journey now

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Today20 Jul
Tomorrow21 Jul
from US$103
Tue22 Jul
Wed23 Jul
from US$103
Thu24 Jul
from US$96
Fri25 Jul
Sat26 Jul
from US$77
Sun27 Jul

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 21 July at
    Departure city: Florence
    Departure location: Bus station
    Arrival time: 22 July at
    Destination city: Philadelphia
    Destination location: Philadelphia, 199 Spring Garden St
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 21 July at
    Departure city: Florence
    Departure location: Florence, SC
    Arrival time: 21 July at
    Destination city: Philadelphia
    Destination location: Philadelphia, 199 Spring Garden St
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: 21 July at
    Departure city: Florence
    Departure location: Bus station
    Arrival time: 22 July at
    Destination city: Philadelphia
    Destination location: 199 Spring Garden St.
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 21 July at
    Departure city: Florence
    Departure location: Florence, SC
    Arrival time: 21 July at
    Destination city: Philadelphia
    Destination location: Philadelphia, 199 Spring Garden St
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: 21 July at
    Departure city: Florence
    Departure location: Bus station
    Arrival time: 22 July at
    Destination city: Philadelphia
    Destination location: Philadelphia (Logan Square)
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Compare 2 ways to travel from Florence to Philadelphia

Bus
Average priceUS$68 - US$243Average duration17h 15m
19kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average priceUS$91 - US$312Average duration10h 18m
69kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from Florence to Philadelphia

Among the sustainable travel choices, the train stands out as a good way to reach Philadelphia. The journey takes about 10 hours 18 minutes and with fares starting at just US$91, it presents an excellent value for a comfortable ride.

1train per day
10h 18mAverage duration
US$91Cheapest ticket
69kgCO₂ emissions

Bus Florence to Philadelphia: Trip Overview

Average ticket priceUS$119
Average bus trip duration17h 15m
Number of daily buses9
Earliest bus departure00:05
Distance472 miles
Latest bus departure16:15

Florence to Philadelphia Bus

Busbud helps you find a bus from Florence to Philadelphia. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Florence to Philadelphia.

From cheap bus tickets to more luxurious buses travelling from Florence to Philadelphia, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Florence, SC, US - Philadelphia, PA

  1. What's the distance between Florence and Philadelphia by coach?

    The distance between Florence and Philadelphia by coach is approximately 467 miles (753 km).

  2. What is the best way to go from Florence to Philadelphia without flying?

    You have the option to select the coach for your journey on this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
18/07
US$113
19/07
US$102
Today
US$96
21/07
US$96
22/07
US$77
23/07
US$96
24/07
US$89
25/07
US$75
busbud logoThe cheapest trip from Florence to Philadelphia was searched and found on 25 Jul 2025 with a price of US$75

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence to Philadelphia as early as possible.

You can expect to pay from US$75 to US$242 for a bus ticket from Florence to Philadelphia based on the last 2 days. You can expect to find the cheapest price for the trip at US$75, which is on 2025-07-25.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Florence and Philadelphia!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Florence to Philadelphia.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Florence to Philadelphia that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Florence to Philadelphia.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

What's the cheapest way to go from Florence to Philadelphia?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Florence by bus?

Bus from Florence to Philadelphia

You can also go to Philadelphia, PA by train

Train from Florence, SC, US to Philadelphia, PA

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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