Find coaches from Florence, SC, US to Philadelphia, PA

Next departures

Next departures from Florence to Philadelphia on 2 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
    		Bus station
    		Camden (Walter Rand Transportation Center)Cheapest
    FlixBus
      		Florence, SC
      		Philadelphia, 199 Spring Garden StFastest
      Greyhound Lines, Inc. + FlixBus
        		Bus station
        		199 Spring Garden St.No tags
        FlixBus
          		Florence, SC
          		Cherry Hill MallNo tags
          Greyhound Lines, Inc. + FlixBus
            		Bus station
            		Philadelphia, 199 Spring Garden StNo tags

            Last refresh of the prices: Today at 10:25 AM EDT.

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            Compare 2 ways to travel from Florence to Philadelphia

            We recommend taking the train

            Among the sustainable travel choices, the train stands out as a good way to reach Philadelphia. The journey takes about 10 hours 18 minutes and with fares starting at just US$91, it presents an excellent value for a comfortable ride.

            1train per day
            10h 18mAverage duration
            758 kmDistance
            69kgCO₂ emissions
            Bus
            		Average priceUS$57 - US$238Average duration19h
            19kg CO₂e
            Train
            		Average priceUS$91 - US$356Average duration10h 18m
            69kg CO₂e

            Bus Florence, SC, US to Philadelphia, PA: Trip Overview

            Average ticket priceUS$95
            Average bus trip duration19h
            Number of daily buses12
            Earliest bus departure00:05
            Distance761 km
            Latest bus departure16:15

            Florence to Philadelphia Bus

            Busbud helps you find a bus from Florence to Philadelphia. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

            We make it our job to connect you with the most dependable bus companies that cover bus service from Florence to Philadelphia.

            From cheap bus tickets to more luxurious buses travelling from Florence to Philadelphia, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

            Frequently asked questions on the trip Florence, SC, US - Philadelphia, PA

            1. How much does a bus ticket from Florence to Philadelphia cost?

              The bus ticket price from Florence to Philadelphia starts at US$57. The best way to find cheap bus tickets from Florence to Philadelphia is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

            2. How long is the bus ride from Florence to Philadelphia?

              The average travel time between Florence and Philadelphia is around 19h, although the fastest bus will take about 11h 40m. This is the time it takes to travel the 753 km that separates the two cities.

            3. How many daily bus connections are there between Florence and Philadelphia?

              The number of buses from Florence to Philadelphia can differ depending on the day of the week. On average, there are 12 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Florence to Philadelphia by comparing and selecting the bus that fits your travel style and budget on Busbud.

            4. Which bus companies travel from Florence to Philadelphia?

              When taking the bus from Florence to Philadelphia, you can travel comfortably and safely with FlixBus, Greyhound.

            5. What are the departure and arrival stations when taking the bus from Florence to Philadelphia?

              Buses travelling between Florence and Philadelphia leave from Florence Bus Station or TA Travel Center - Florence and arrive at Philadelphia Airport, Independence Travel Center, #2842 St.Vincent St.

            Find cheapest prices for buses

            Price is for a one-way ticket for one passenger and based on past searches.

            Best price found
            30/10
            US$119
            31/10
            US$94
            Today
            US$117
            02/11
            US$107
            03/11
            US$75
            04/11
            US$78
            05/11
            US$76
            06/11
            US$75
            busbud logoThe cheapest trip from Florence, SC, US to Philadelphia, PA was searched and found on 03 Nov 2025 with a price of US$75

            To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Philadelphia, PA as early as possible.

            You can expect to pay from US$75 to US$147 for a bus ticket from Florence, SC, US to Philadelphia, PA based on the last 2 days. You can expect to find the cheapest price for the trip at US$75, which is on 2025-11-03.

            Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

            About Bus Travel

            Bus Travel Tips

            Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Florence and Philadelphia!

            From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Florence to Philadelphia.

            Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Florence to Philadelphia that are otherwise impossible to come by with a plane.

            Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Florence to Philadelphia.

            Did you know?

            Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

            One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

            Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

            What's the cheapest way to go from Florence, SC, US to Philadelphia, PA?

            busbud logoThe bus is the cheapest travel choice for this destination

            Will you be returning to Florence, SC, US by bus?

            Bus from Philadelphia, PA to Florence, SC, US

            You can also go to Philadelphia, PA by train

            Train from Florence, SC, US to Philadelphia, PA

            Why choose Busbud?

            The Best Way To Book Bus and Train Tickets

            Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

            People from around the world trust Busbud

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