What is the distance between Florence and Philadelphia?

The distance separating Florence and Philadelphia is 467 miles (753 km).

What are the departure and arrival stations when taking the bus from Florence to Philadelphia?

If you're headed to Philadelphia from Florence, chances are that your bus will leave from Florence Bus Station and arrive at Philadelphia Airport. These are the most popular departure and arrival locations on this route, there are other pick-up and drop-off locations that could make it easier for you to reach your destination.

What are the best sights and things to do in Philadelphia?

Once in Philadelphia, you can start exploring the city and discover its surroundings. The top sights and things to do are Please Touch Museum, Arden Theatre Company, Love Park, The Franklin Institute and Betsy Ross House.

Bus Florence to Philadelphia from $69 | Refundable Tickets

Next bus departures

Next departures for Florence to Philadelphia on November 15
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	4:30pm	Bus station	14h 15m	6:45am	199 Spring Garden St.	Cheapest
	Bus	12:05am	Florence, SC	11h 40m	11:45am	Philadelphia, 199 Spring Garden St	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	4:30pm	Bus station	16h 15m	8:45am	Philadelphia, 199 Spring Garden St	No tags
	Bus	4:30pm	Bus station	22h 5m	2:35pm	Camden (Walter Rand Transportation Center)	No tags
	Bus	12:05am	Florence, SC	19h	7:05pm	Cherry Hill Mall	No tags

Next departures for Florence to Philadelphia on November 16
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	4:30pm	Bus station	14h 15m	6:45am	199 Spring Garden St.	Cheapest
	Bus	12:05am	Florence, SC	11h 40m	11:45am	Philadelphia, 199 Spring Garden St	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	4:30pm	Bus station	16h 15m	8:45am	Philadelphia, 199 Spring Garden St	No tags
	Bus	4:30pm	Bus station	22h 5m	2:35pm	Camden (Walter Rand Transportation Center)	No tags
	Bus	12:05am	Florence, SC	19h	7:05pm	Cherry Hill Mall	No tags

Next departures for Florence to Philadelphia on November 17
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	4:30pm	Bus station	14h 15m	6:45am	199 Spring Garden St.	Cheapest
	Bus	12:05am	Florence, SC	11h 40m	11:45am	Philadelphia, 199 Spring Garden St	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	4:30pm	Bus station	16h 15m	8:45am	Philadelphia, 199 Spring Garden St	No tags
	Bus	4:30pm	Bus station	22h 5m	2:35pm	Camden (Walter Rand Transportation Center)	No tags
	Bus	12:05am	Florence, SC	19h	7:05pm	Cherry Hill Mall	No tags

Next departures for Florence to Philadelphia on November 18
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	4:30pm	Bus station	16h 15m	8:45am	Philadelphia, 199 Spring Garden St	Cheapest
	Bus	12:05am	Florence, SC	12h 55m	1:00pm	Philadelphia, 199 Spring Garden St	Fastest
	Bus	4:30pm	Bus station	14h 15m	6:45am	199 Spring Garden St.	No tags
Greyhound Lines, Inc. + FlixBus	Bus	4:30pm	Bus station	22h 40m	3:10pm	Cherry Hill Mall	No tags
	Bus	12:05am	Florence, SC	20h 35m	8:40pm	Cherry Hill Mall	No tags

Next departures for Florence to Philadelphia on November 20
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	4:30pm	Bus station	19h	11:30am	Schuylkill & Walnut	Cheapest
Greyhound Lines, Inc. + FlixBus	Bus	4:30pm	Bus station	14h 15m	6:45am	199 Spring Garden St.	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	4:30pm	Bus station	16h 15m	8:45am	Philadelphia, 199 Spring Garden St	No tags
	Bus	4:30pm	Bus station	22h 5m	2:35pm	Camden (Walter Rand Transportation Center)	No tags
Greyhound Lines, Inc. + FlixBus	Bus	4:30pm	Bus station	19h 10m	11:40am	Cherry Hill Mall	No tags

Last refresh of the prices: Last Tuesday at 4:36 PM EST.

Compare 2 ways to go from Florence to Philadelphia

We recommend taking the train

Among the sustainable travel choices, the train stands out as the good way to reach Philadelphia. The journey takes about 10 hours 18 minutes and with fares starting at just $91, it presents an excellent value for a comfortable ride.

1train per day

10h 18mAverage Duration

470 milesDistance

69kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$57 - $238	Average Duration19h	CO₂ emissions 19kg CO₂e
Train	Average Price$91 - $356	Average Duration10h 18m	CO₂ emissions 69kg CO₂e

Compare bus companies

FlixBus

3.5/511,311 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/587,371 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Where are the popular stops in Florence and Philadelphia?

Stops in Florence

A - Florence Bus Station

B - TA Travel Center - Florence

Stops in Philadelphia

A - Philadelphia Airport

B - Independence Travel Center

C - #2842 St.Vincent St

D - Bus Station

E - Island Av & Suffolk Av MBFS

F - NRG SEPTA Station

Frequently asked questions about traveling from Florence, SC, US to Philadelphia, PA by bus

What is the distance between Florence and Philadelphia?
What are the departure and arrival stations when taking the bus from Florence to Philadelphia?
What are the best sights and things to do in Philadelphia?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/12

$85

11/13

$130

Today

$117

11/15

$74

11/16

$88

11/17

$79

11/18

$79

11/19

$76

The cheapest trip from Florence, SC, US to Philadelphia, PA was searched and found on Nov 15, 2025 with a price of $74

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Philadelphia, PA, as early as possible.

You can expect to pay from $74 to $131 for a bus ticket from Florence, SC, US to Philadelphia, PA based on the last 2 days. You can expect to find the cheapest price for the trip at $74 which is on 2025-11-15.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.