Bus from Florence, SC, US to Philadelphia, PA: Tickets & Schedules

Next bus departures

Next departures for Florence to Philadelphia on January 1
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc. + FlixBus
Bus
Bus station
Philadelphia, 199 Spring Garden StCheapest
Greyhound Lines, Inc. + FlixBus
Bus
Bus station
199 Spring Garden St.Fastest
Greyhound Lines, Inc. + FlixBus
Bus
Bus station
Cherry Hill MallNo tags
Greyhound Lines, Inc.Bus
Bus station
Camden (Walter Rand Transportation Center)No tags
Greyhound Lines, Inc. + FlixBus
Bus
Bus station
Frazer - 56-40 Matthews RdNo tags

Last refresh of the prices: Last Sunday at 4:41 PM EST.

Compare 2 ways to go from Florence to Philadelphia

We recommend taking the train

Among the sustainable travel choices, the train stands out as the good way to reach Philadelphia. The journey takes about 10 hours 57 minutes and with fares starting at just $91, it presents an excellent value for a comfortable ride.

2train per day
10h 57mAverage Duration
470 milesDistance
69kgCO₂ emissions
Average Price$66 - $245Average Duration18h 10m
19kg CO₂e
Average Price$91 - $457Average Duration10h 57m
69kg CO₂e

Frequently asked questions about traveling from Florence, SC, US to Philadelphia, PA by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Florence to Philadelphia?

    The cheapest bus tickets from Florence to Philadelphia start from $66. The average price for this route is around $119. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Florence to Philadelphia?

    The average bus trip duration from Florence to Philadelphia is 18h 10m, covering a distance of 473 miles (762 km). The quickest bus can get you there in 11h 40m and is operated by FlixBus.

  3. Which bus companies service the Florence to Philadelphia route?

    Several major bus companies operate on this route with 12 buses available per day, including services from FlixBus, Greyhound.

  4. What is the earliest and latest departure time for the bus from Florence to Philadelphia?

    The earliest bus departs from Florence to Philadelphia at 12:05am. And the latest bus departs at 4:30pm.

  5. What are the CO₂ emissions for the bus trip from Florence to Philadelphia?

    A bus trip from Florence to Philadelphia generates an estimated 19 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

  6. What is the best bus company from Florence to Philadelphia?

    According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11648 reviews.

  7. Which bus company has the best Wi-Fi from Florence to Philadelphia?

    Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

  8. Which bus company has the most timely service from Florence to Philadelphia?

    According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from Florence to Philadelphia?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
12/29
$185
12/30
$143
Today
$143
busbud logoThe cheapest trip from Florence, SC, US to Philadelphia, PA was searched and found on Dec 30, 2025 with a price of $143

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Philadelphia, PA, as early as possible.

What's the cheapest way to go from Florence, SC, US to Philadelphia, PA?

busbud logoThe bus is the cheapest travel choice for this destination

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