- Florence to Philadelphia buses
Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Florence, SC | Schuylkill & Walnut | Cheapest | ||||
![]() | Bus | Florence, SC | Philadelphia, 199 Spring Garden St | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Bus station | 199 Spring Garden St. | No tags | ||||
![]() | Bus | Bus station | Camden (Walter Rand Transportation Center) | No tags | ||||
![]() | Bus | Florence, SC | Cherry Hill Mall | No tags |
Last refresh of the prices: Today at 1:07 AM EST.
Compare 2 ways to go from Florence to Philadelphia
Among the sustainable travel choices, the train stands out as the good way to reach Philadelphia. The journey takes about 10 hours 57 minutes and with fares starting at just $91, it presents an excellent value for a comfortable ride.
Where are the popular stops in Florence and Philadelphia?
Stops in Florence
- A619 S Irby St, Florence, SC 29501, USA
- B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Stops in Philadelphia
- BOff of Race Street between 5th Street and, N 6th St, Philadelphia, PA 19106, USA
- C
#2842 St.Vincent St
15th St Trolley Station, Philadelphia, PA 19102, USA - D
Bus Station
1001 Filbert St, Philadelphia, PA 19107, USA - E
Island Av & Suffolk Av MBFS
3000 Island Ave, Philadelphia, PA 19153, USA - F
NRG SEPTA Station
3701 Broad St, Philadelphia, PA 19148, USA
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Frequently asked questions about traveling from Florence, SC, US to Philadelphia, PA by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Florence to Philadelphia?
The cheapest bus tickets from Florence to Philadelphia start from $60. The average price for this route is around $101. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Florence to Philadelphia?
The average bus trip duration from Florence to Philadelphia is 19h, covering a distance of 472 miles (762 km). The quickest bus can get you there in 11h 40m and is operated by FlixBus.
Which bus companies service the Florence to Philadelphia route?
What is the earliest and latest departure time for the bus from Florence to Philadelphia?
The earliest bus departs from Florence to Philadelphia at 12:05am. And the latest bus departs at 4:30pm.
What are the CO₂ emissions for the bus trip from Florence to Philadelphia?
A bus trip from Florence to Philadelphia generates an estimated 19 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Florence to Philadelphia?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11380 reviews.
Which bus company has the best Wi-Fi from Florence to Philadelphia?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Florence to Philadelphia?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Florence to Philadelphia?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Philadelphia, PA, as early as possible.
You can expect to pay from $96 to $258 for a bus ticket from Florence, SC, US to Philadelphia, PA based on the last 2 days. You can expect to find the cheapest price for the trip at $96 which is on 2025-12-01.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.








