Next available departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Parcheggio Via Pietransantina | Lampugnano bus station | Cheapest | |||||
 | Piazza della Stazione, 10 | Milano Centrale | Fastest | |||||
| Piazza della Stazione, 10 | Milano Centrale | No tags | |||||
| park Aurelia | Milan (Malpensa Airport Terminal 1) | No tags | |||||
| Piazza della Stazione, 10 | Milano Centrale | No tags |
Last refresh of the prices: Today at 20:16 CEST.
Compare 2 ways to travel from Pisa to Milano
Among the sustainable travel choices, the Bus stands out as a good way to reach Milano. The journey takes about 5 hours 50 minutes and with fares starting at just R$104, it presents an excellent value for a comfortable ride.
Where are the popular stops in Pisa and Milano?
Stops in Pisa
- APiazza della Stazione, 10, 56125 Pisa PI, Italy
- CVia Pietrasantina, 56123 Pisa PI
- D
Stazione Ferroviaria Pisa Centrale - Fermata dell'autobus
Via Giuseppe Sainati 16, 56121 Pisa PI, Italy - E
Tombolo
Via Aurelia, 325, 56121 Pisa PI, Italy - F
San Rossore
56122 Pisa PI, Italy
Stops in Milano
- APiazza Duca d'Aosta 1, 20124 Milano MI, Italy
- BVia Gamboloita 7, 20139 Milano MI, Italy
- C20017 Rho MI, Italy
- DPiazza I Maggio, 1, 20099 Sesto San Giovanni MI, Italy
- EVia Giulio Natta, 228, 20151 Milano, Italy
- FP.za Sigmund Freud 1, 20124 Milano MI, Italy
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Frequently asked questions about travelling from Pisa to Milano by bus or train
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much does a ticket from Pisa to Milano cost?
The cheapest tickets from Pisa to Milano start from R$103. The average price for this route is around R$240. Busbud recommends that you book your tickets in advance for a better chance of getting the lowest possible price.
How long is the journey from Pisa to Milano?
The average trip duration from Pisa to Milano is 5h 25m, covering a distance of 138 miles. The quickest vehicle can get you there in 3h 44m and is operated by Trenitalia.
Which companies operate the Pisa to Milano route?
Several major companies operate on this route with 7 trips available per day, including services from FlixBus, Itabus, Trenitalia.
What are the earliest and latest departure times from Pisa to Milano?
The earliest service departs from Pisa for Milano at 04:45. And the latest service departs at 23:30.
What are the CO₂ emissions for the journey from Pisa to Milano?
A journey from Pisa to Milano produces an estimated 5.53925 kg of CO₂, making it a highly eco-friendly way to travel and a mode of transport recommended by Busbud.
Which is the best company from Pisa to Milano?
According to Busbud customers, the highest-rated company on this route is Trenitalia, with an average rating of 3.9 out of 5 stars based on 58 reviews.
Which company has the best Wi-Fi from Pisa to Milano?
According to reviews on Busbud, the company Itabus has the best Wi-Fi rating with a score of 3.0.
Which company offers the most punctual service from Pisa to Milano?
According to Busbud traveller reviews, the most punctual company on this route is Trenitalia, with a punctuality rating of 4.6 out of 5 stars.
Which company has the cleanest vehicles from Pisa to Milano?
According to Busbud traveller reviews, the company with the cleanest vehicles on this route is Trenitalia, with a cleanliness rating of 4.7 out of 5 stars.
Find the cheapest prices for buses and trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Pisa to Milano was searched and found on 6 May 2026 with a price of R$90To save money and ensure you get the best seat, it's a good idea to buy your bus and train tickets from Pisa to Milano, as early as possible.
You can expect to pay between R$90 and R$437 for a bus or train ticket from Pisa to Milano based on the past 2 days. You can expect to find the lowest price for the trip at R$90 on 2026-05-06.
Usually Trenitalia will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
