Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Depew Station | Gateway Station | No tags | ||||
| Train | Depew Station | Gateway Station | No tags | ||||
| Train | Depew Station | Gateway Station | No tags | ||||
| Train | Depew Station | Gateway Station | No tags | ||||
| Train | Depew Station | Gateway Station | No tags |
Compare 2 ways to travel from Buffalo to St. Louis
Among the sustainable travel choices, the Train stands out as a good way to reach St. Louis. The journey takes about 19 hours 46 minutes and with fares starting at just CA$131, it presents an excellent value for a comfortable ride.
Where are the popular train stations and stops in Buffalo, NY and St. Louis?
Train Companies
Based on 5791 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the Wi‑Fi. Amtrak ticket prices on this trip start at CA$131
Frequently asked questions about travelling from Buffalo, NY to St. Louis by train
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much does a train ticket cost from Buffalo to St. Louis?
The cheapest train tickets from Buffalo to St. Louis start from CA$131. The average price for this train route is around CA$359. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the train journey from Buffalo to St. Louis?
The average train journey time from Buffalo to St. Louis is 19h 46m, covering a distance of 668 miles. The fastest train gets you there in 19h 46m and is operated by Amtrak.
Which train operators serve the Buffalo to St. Louis route?
Several major train operators run on this route with 1 trains available per day.
What are the earliest and latest departure times for the train from Buffalo to St. Louis?
The earliest train from Buffalo to St. Louis departs at 00:39. And the latest train departs at 00:39.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Buffalo, NY to St. Louis was searched and found on 27 Apr 2026 with a price of CA$336To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Buffalo, NY to St. Louis as early as possible.
