Next train departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Depew Station | Gateway Station | Cheapest | ||||
| Train | Depew Station | Gateway Station | Fastest | ||||
| Train | Depew Station | Gateway Station | No tags | ||||
| Train | Depew Station | Gateway Station | No tags | ||||
| Train | Depew Station | Gateway Station | No tags |
Last refresh of the prices: Yesterday at 11:39 AM EST.
Compare 2 ways to travel from Buffalo to St. Louis
Among the sustainable travel choices, the train stands out as a good way to reach St. Louis. The journey takes about 19 hours 28 minutes and with fares starting at just R 2 972, it presents an excellent value for a comfortable ride.
Where are the popular train stations and stops in Buffalo, NY and St. Louis?
Train Companies
Based on 5644 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the Wi-Fi. Amtrak ticket prices on this trip start at R 2 972
Frequently asked questions about travelling from Buffalo, NY to St. Louis by train
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the train ticket from Buffalo to St. Louis?
The cheapest train tickets from Buffalo to St. Louis start from R 2 972. The average price for this train route is around R 4 403. Busbud recommends booking your tickets in advance for a better chance to secure the lowest possible price.
How long is the train journey from Buffalo to St. Louis?
The average train journey time from Buffalo to St. Louis is 19h 28m, covering a distance of 1077 km. The quickest train can get you there in 19h 28m and is operated by Amtrak.
Which train operators serve the Buffalo to St. Louis route?
Several major train operators run on this route, with 1 trains available per day.
What are the earliest and latest departure times for the train from Buffalo to St. Louis?
The earliest train from Buffalo to St. Louis departs at 00:39. And the latest train departs at 00:39.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Buffalo, NY to St. Louis was searched and found on 14 Dec 2025 with a price of R 1 746To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Buffalo, NY to St. Louis as early as possible.
You can expect to pay from R 1 746 to R 16 709 for a train ticket from Buffalo, NY to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at R 3 370, which is on 2025-12-17.
