Train from Detroit, MI to Greenville, SC: Tickets & Timetables

Previously seen journeys

Next departures from Detroit to Greenville on 12 December
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
AmtrakTrain
Amtrak Station
Greenville StationNo tags
AmtrakTrain
Amtrak Station
Greenville StationNo tags
AmtrakTrain
Amtrak Station
Greenville StationNo tags
AmtrakTrain
Amtrak Station
Greenville StationNo tags
AmtrakTrain
Amtrak Station
Greenville StationNo tags

Compare 2 ways to travel from Detroit to Greenville

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 1 day, 3 hours 25 minutes and with fares starting at just £81, it presents an excellent value for a comfortable ride.

4bus per day
1d 3hAverage duration
519 milesDistance
21kgCO₂ emissions
Average price£81 - £352Average duration1d 3h
21kg CO₂e
Average price£269 - £406Average duration1d 19h
76kg CO₂e

Frequently asked questions about travelling from Detroit, MI to Greenville, SC by train

Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.

  1. How much does a train ticket cost from Detroit to Greenville?

    The cheapest train tickets from Detroit to Greenville start from £269. The average price for this train route is around £315. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.

  2. How long is the train journey from Detroit to Greenville?

    The average train journey time from Detroit to Greenville is 1d 19h, covering a distance of 519 miles. The fastest train gets you there in 1d 19h and is operated by Amtrak.

  3. Which train operators serve the Detroit to Greenville route?

    Several major train operators run on this route with 1 trains available per day.

  4. What are the earliest and latest departure times for the train from Detroit to Greenville?

    The earliest train from Detroit to Greenville departs at 09:35. And the latest train departs at 09:35.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
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Today
£363
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busbud logoThe cheapest trip from Detroit, MI to Greenville, SC was searched and found on 12 Dec 2025 with a price of £363

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Detroit, MI to Greenville, SC as early as possible.

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