How much is the train ticket from Detroit to Greenville?

The cheapest train tickets from Detroit to Greenville start from $222. The average price for this train route is around $363. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the train journey from Detroit to Greenville?

The average train ride duration from Detroit to Greenville is 1d 19h, covering a distance of 519 miles (837 km). The quickest train can get you there in 1d 19h and is operated by Amtrak .

Which train operators service the Detroit to Greenville route?

Several major train operators operate on this route with 1 trains available per day.

What is the earliest and latest departure time for the train from Detroit to Greenville?

The earliest train departs from Detroit to Greenville at 9:35am. And the latest train departs at 9:35am.

Train Detroit to Greenville from $275 | Refundable Tickets

Next train departures

Next departures for Detroit to Greenville on February 3
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	9:35am	Amtrak Station	1d 19h	5:24am	Greenville Station	Cheapest
Train	9:35am	Amtrak Station	1d 19h	5:24am	Greenville Station	Fastest
Train	9:35am	Amtrak Station	1d 19h	5:24am	Greenville Station	No tags
Train	9:35am	Amtrak Station	1d 19h	5:24am	Greenville Station	No tags
Train	9:35am	Amtrak Station	1d 19h	5:24am	Greenville Station	No tags

Next departures for Detroit to Greenville on February 4
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	9:35am	Amtrak Station	1d 19h	5:24am	Greenville Station	CheapestFastest
Train	9:35am	Amtrak Station	1d 19h	5:24am	Greenville Station	No tags
Train	9:35am	Amtrak Station	1d 19h	5:24am	Greenville Station	No tags

Next departures for Detroit to Greenville on February 5
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	9:35am	Amtrak Station	1d 19h	5:24am	Greenville Station	Cheapest
Train	9:35am	Amtrak Station	1d 19h	5:24am	Greenville Station	Fastest
Train	9:35am	Amtrak Station	1d 19h	5:24am	Greenville Station	No tags
Train	9:35am	Amtrak Station	1d 19h	5:24am	Greenville Station	No tags
Train	9:35am	Amtrak Station	1d 19h	5:24am	Greenville Station	No tags

Next departures for Detroit to Greenville on February 6
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	9:35am	Amtrak Station	1d 19h	5:24am	Greenville Station	CheapestFastest
Train	9:35am	Amtrak Station	1d 19h	5:24am	Greenville Station	No tags
Train	9:35am	Amtrak Station	1d 19h	5:24am	Greenville Station	No tags

Next departures for Detroit to Greenville on February 8
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	9:35am	Amtrak Station	1d 19h	5:24am	Greenville Station	CheapestFastest
Train	9:35am	Amtrak Station	1d 19h	5:24am	Greenville Station	No tags
Train	9:35am	Amtrak Station	1d 19h	5:24am	Greenville Station	No tags

Last refresh of the prices: Last Friday at 10:50 PM EST.

Compare 2 ways to go from Detroit to Greenville

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Greenville. The journey takes about 1 day, 25 minutes and with fares starting at just $87, it presents an excellent value for a comfortable ride.

3bus per day

1d Average Duration

519 milesDistance

21kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$87 - $300	Average Duration1d	CO₂ emissions 21kg CO₂e
Train	Average Price$222 - $634	Average Duration1d 19h	CO₂ emissions 76kg CO₂e

Train Companies

Amtrak

4/55,754 reviews

Staff4.7

Timeliness3.8

Cleanliness4.6

Wifi3.6

Based on 5754 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $222

US train companies:Amtrak, Trenitalia, Renfe, VIA Rail Canada, Amtrak Acela, NS Nederlandse Spoorwegen, Iryo

Frequently asked questions about traveling from Detroit, MI to Greenville, SC by train

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the train ticket from Detroit to Greenville?
The cheapest train tickets from Detroit to Greenville start from $222. The average price for this train route is around $363. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the train journey from Detroit to Greenville?
The average train ride duration from Detroit to Greenville is 1d 19h, covering a distance of 519 miles (837 km). The quickest train can get you there in 1d 19h and is operated by Amtrak.
Which train operators service the Detroit to Greenville route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the train from Detroit to Greenville?
The earliest train departs from Detroit to Greenville at 9:35am. And the latest train departs at 9:35am.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

01/31

$275

02/01

$1,082

Today

$336

02/03

$275

02/04

$317

02/05

$298

02/06

$343

02/07

No data

The cheapest trip from Detroit, MI to Greenville, SC was searched and found on Jan 31, 2026 with a price of $275

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Detroit, MI to Greenville, SC, as early as possible.

You can expect to pay from $275 to $1,105 for a train ticket from Detroit, MI to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at $275 which is on 2026-02-03.