Train from Detroit, MI to Greenville, SC: Tickets & Timetables

Next train departures

Next departures from Detroit to Greenville on 3 February
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
AmtrakTrain
Amtrak Station
Greenville StationCheapest
AmtrakTrain
Amtrak Station
Greenville StationFastest
AmtrakTrain
Amtrak Station
Greenville StationNo tags
AmtrakTrain
Amtrak Station
Greenville StationNo tags
AmtrakTrain
Amtrak Station
Greenville StationNo tags

Last refresh of the prices: Last Friday at 22:50 EST.

Compare 2 ways to travel from Detroit to Greenville

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Greenville. The journey takes about 1 day, 25 minutes and with fares starting at just £66, it presents an excellent value for a comfortable ride.

3bus per day
1d Average duration
519 milesDistance
21kgCO₂ emissions
Average price£66 - £225Average duration1d
21kg CO₂e
Average price£167 - £477Average duration1d 19h
76kg CO₂e

Frequently asked questions about travelling from Detroit, MI to Greenville, SC by train

Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.

  1. How much does a train ticket cost from Detroit to Greenville?

    The cheapest train tickets from Detroit to Greenville start from £167. The average price for this train route is around £273. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.

  2. How long is the train journey from Detroit to Greenville?

    The average train journey time from Detroit to Greenville is 1d 19h, covering a distance of 519 miles. The fastest train gets you there in 1d 19h and is operated by Amtrak.

  3. Which train operators serve the Detroit to Greenville route?

    Several major train operators run on this route with 1 trains available per day.

  4. What are the earliest and latest departure times for the train from Detroit to Greenville?

    The earliest train from Detroit to Greenville departs at 09:35. And the latest train departs at 09:35.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
31/01
£207
01/02
£814
Today
£253
03/02
£207
04/02
£239
05/02
£225
06/02
£258
07/02
No data
busbud logoThe cheapest trip from Detroit, MI to Greenville, SC was searched and found on 31 Jan 2026 with a price of £207

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Detroit, MI to Greenville, SC as early as possible.

You can expect to pay from £207 to £832 for a train ticket from Detroit, MI to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at £207, which is on 2026-02-03.

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