Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Harrisburg, PA | Florence Station | CheapestFastest | |||||
| Harrisburg, PA | Florence Station | No tags | |||||
| Harrisburg, PA | Florence Station | No tags |
Accepted payments
Compare 2 ways to travel from Harrisburg to Florence
Busbud recommends taking the bus from Harrisburg to FlorenceAmong the sustainable travel choices, the bus stands out as a good way to reach Florence. The journey takes about 21 hours 40 minutes and with fares starting at just US$80, it presents an excellent value for a comfortable ride.
Train Harrisburg to Florence, SC, US: Trip Overview
Please note, this information is subject to change.
Train Companies
Based on 5415 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the Wi-Fi. Amtrak ticket prices on this trip start at US$258
Harrisburg to Florence Train
With Busbud, comparing and booking tickets for a train from Harrisburg to Florence is a breeze. Browse through an extensive selection of train fares and train schedules to find the best deals.
Train services from Harrisburg to Florence will be provided by the most trusted companies.
Discover how much the train trip from Harrisburg to Florence will cost you. Use our filters and sorting features to find the cheapest train tickets or high-end trains.
Frequently asked questions on the trip Harrisburg - Florence, SC, US
How much does a cheap train ticket from Harrisburg to Florence cost?
The average train ticket price from Harrisburg to Florence is US$258. The best way to find cheap train tickets from Harrisburg to Florence is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the train trip from Harrisburg to Florence?
A train trip between Harrisburg and Florence is around 14h 5m, although the fastest train will take about 14h 5m. This is the time it takes to travel the 446 miles that separates the two cities.
How many daily train are there between Harrisburg and Florence?
The number of trains from Harrisburg to Florence can differ depending on the day of the week. On average, there is 1. Some trains are direct while others have layovers. Simplify your train trip from Harrisburg to Florence by comparing and selecting the train that fits your travel style and budget on Busbud.
Which train companies travel from Harrisburg to Florence?
When taking the train from Harrisburg to Florence, you can travel comfortably and safely with Amtrak.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Harrisburg to Florence, SC, US was searched and found on 26 Aug 2025 with a price of US$144To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Harrisburg to Florence, SC, US as early as possible.
You can expect to pay from US$144 to US$653 for a train ticket from Harrisburg to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$144, which is on 2025-08-26.
About Train Travel
Train Travel Tips
Taking the fastest trains allows you to travel at speeds greater than 300 km/h. Taking a trip from Harrisburg to Florence is not only much quicker but more comfortable too! You can usually travel directly to the city centre and save time while you're at it.
No matter if you plan to take a regional or high-speed train to Florence, the planet will thank you. You’ll help to protect the beautiful landscapes that will unfold before your very eyes.
With up to 30x less CO2 emissions for your train journey between Harrisburg and Florence, the train is an ecological alternative to flights or personal cars.
Make a music playlist for your train ride from Harrisburg to Florence and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
New York holds the record for the most platforms and track numbers in a single station. Grand Central Station in Manhattan is one of the largest rail terminals in the world with more than 44 platforms and 67 tracks to accommodate passengers.
Some trains in Sweden can recover more than a fifth of the energy they use by braking. This is especially true with ore trains as they descend from Narvik to Kiruna.
The magnetic levitation train (Maglev for short) is currently the fastest train in the world. With a speed of 603 km/ h, it is closely followed by the French high-speed train (574.8 km / h) which remains in 2020, the fastest train to date
Top Travelled Train Routes
Why choose Busbud?
The Best Way To Book Bus and Train Tickets
Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
People from around the world trust Busbud
Popular Trains Connecting Harrisburg
Trains Leaving from Harrisburg
Popular Trains Connecting Florence
Trains Going to Florence
Popular train trips
Top Routes Worldwide
- Train from Wells to Fargo
- Train from Richmond to Richmond
- Train from Waterloo to Buffalo
- Train from Niagara Falls to Ontario
- Train from Washington to Everett
- Train from Buffalo to New York City
- Train from Seattle to Washington
- Train from Rochester to New York City
- Train from Jacksonville to Jacksonville
- Train from Ventura to Simi Valley
- Train from Newark to Essex
- Train from Fayetteville to Cumberland
- Train from Bellingham to Washington
- Train from Oxnard to Ventura
- Train from Newark to Essex