Train tickets from Harrisburg to Florence, SC, US

Previously seen trips

Next departures for Harrisburg to Florence on November 3
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Amtrak
    Harrisburg, PA
    Florence StationNo tags
    Amtrak
      Harrisburg, PA
      Florence StationNo tags
      Amtrak
        Harrisburg, PA
        Florence StationNo tags
        Amtrak
          Harrisburg, PA
          Florence StationNo tags
          Amtrak
            Harrisburg, PA
            Florence StationNo tags

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            Compare 2 ways to go from Harrisburg to Florence

            We recommend taking the train

            Among the sustainable travel choices, the train stands out as the good way to reach Florence. The journey takes about 14 hours 5 minutes and with fares starting at just $172, it presents an excellent value for a comfortable ride.

            1train per day
            14h 5mAverage Duration
            447 milesDistance
            66kgCO₂ emissions
            Average Price$77 - $234Average Duration22h 5m
            18kg CO₂e
            Average Price$172 - $343Average Duration14h 5m
            66kg CO₂e

            Train Harrisburg to Florence, SC, US: Trip Overview

            Please note, this information is subject to change.

            Average ticket price$196
            Average train trip duration14h 5m
            Number of daily trains1
            Earliest train departure5:00am
            Distance448 miles (721 km)
            Latest train departure1:05pm

            Harrisburg to Florence Train

            With Busbud, comparing and booking tickets for a train from Harrisburg to Florence is a breeze. Browse through an extensive selection of train fares and train schedules to find the best deals.

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            Discover how much the train trip from Harrisburg to Florence will cost you. Use our filters and sorting features to find the cheapest train tickets or high-end trains.

            Frequently asked questions for your trip Harrisburg - Florence, SC, US

            Find cheapest prices for trains

            Price is for a one-way ticket for one passenger and based on past searches.

            Best price found
            11/01
            $171
            11/02
            $298
            Today
            $171
            11/04
            No data
            11/05
            No data
            11/06
            No data
            11/07
            No data
            11/08
            No data
            busbud logoThe cheapest trip from Harrisburg to Florence, SC, US was searched and found on Nov 1, 2025 with a price of $171

            To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Harrisburg to Florence, SC, US, as early as possible.

            About Train Travel

            Train Travel Tips

            Taking the fastest trains allows you to travel at speeds greater than 300 km/h. Taking a trip from Harrisburg to Florence is not only much quicker but more comfortable too! You can usually travel directly to the city centre and save time while you're at it.

            No matter if you plan to take a regional or high-speed train to Florence, the planet will thank you. You’ll help to protect the beautiful landscapes that will unfold before your very eyes.

            With up to 30x less CO2 emissions for your train journey between Harrisburg and Florence, the train is an ecological alternative to flights or personal cars.

            Make a music playlist for your train ride from Harrisburg to Florence, and enjoy the scenery to tunes from your own personal soundtrack.

            Did you know?

            New York holds the record for the most platforms and track numbers in a single station. Grand Central Station in Manhattan is one of the largest rail terminals in the world with more than 44 platforms and 67 tracks to accommodate passengers.

            Some trains in Sweden can recover more than a fifth of the energy they use by braking. This is especially true with ore trains as they descend from Narvik to Kiruna.

            The magnetic levitation train (Maglev for short) is currently the fastest train in the world. With a speed of 603 km/ h, it is closely followed by the French high-speed train (574.8 km / h) which remains in 2020, the fastest train to date

            Will you be returning to Harrisburg by train?

            Train from Florence, SC, US to Harrisburg

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