Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Price and booking link |
|---|---|---|---|---|---|---|---|
FlixBus + Greyhound | Bus
| Florence, SC | Syracuse (Regional Transportation Center) | ||||
Greyhound + FlixBus | Bus
| Florence, SC | Syracuse (Regional Transportation Center) | ||||
Greyhound + FlixBus | Bus
| Bus station | Syracuse (Regional Transportation Center) | ||||
Greyhound + FlixBus | Bus
| Florence, SC | Syracuse (Regional Transportation Center) | ||||
FlixBus + Greyhound | Bus
| Florence, SC | Syracuse (Regional Transportation Center) |
Compare 2 ways to travel from Florence to Syracuse
Among the sustainable travel choices, the Bus stands out as a good way to reach Syracuse. The journey takes about 22 hours 15 minutes and with fares starting at just €75, it presents an excellent value for a comfortable ride.
Bus stations and stops in Florence and Syracuse
Stops in Florence
- A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA - B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Stops in Syracuse
- A
Regional Transportation Center
1 Walsh Circle Ste 30, Syracuse, NY 13208 - C
Syracuse University
Bus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210 - D
Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA - E
New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA - F
Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA
Compare bus companies
Based on 88242 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at €95
Frequently asked questions about travelling by bus from Florence, SC, US to Syracuse, US
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Florence to Syracuse?
The cheapest coach tickets from Florence to Syracuse start from €75. The average price for this route is around €106. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Florence to Syracuse?
The average bus journey time from Florence to Syracuse is 22h 15m, covering a distance of 1036 km. The fastest bus can take you there in 22h 25m and is operated by Greyhound.
Which bus companies service the Florence to Syracuse route?
Several major bus companies operate on this route with 4 buses available per day.
What is the earliest and latest departure time for the bus from Florence to Syracuse?
The earliest bus departs from Florence to Syracuse at 00:05. And the latest bus departs at 19:20.
What are the CO₂ emissions for the bus trip from Florence to Syracuse?
A bus journey from Florence to Syracuse produces an estimated 25.8964 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Florence, SC, US to Syracuse, US was searched and found on 20 Oct 2026 with a price of €99To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Syracuse, US as early as possible.
You can expect to pay from €99 to €99 for a bus ticket from Florence, SC, US to Syracuse, US based on the last 2 days. You can expect to find the cheapest price for the trip at €99, which is on 2026-10-20.
What's the cheapest way to go from Florence, SC, US to Syracuse, US?
The Bus is the cheapest travel choice for this destination
