Previously seen journeys

Next departures from Florence to Syracuse on 27 September
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location
FlixBus + Greyhound	Bus Wi‑Fi Toilet Power outlets	00:05	Florence, SC	19h 25m	19:30	Syracuse (Regional Transportation Center)
Greyhound + FlixBus	Bus Wi‑Fi Toilet Power outlets	00:05	Florence, SC	19h 25m	19:30	Syracuse (Regional Transportation Center)
FlixBus + Greyhound	Bus Wi‑Fi Toilet Power outlets	05:45	Florence, SC	1d 9h	15:15	Syracuse (Regional Transportation Center)
FlixBus + Greyhound	Bus Wi‑Fi Toilet Power outlets	16:15	Bus station	21h 30m	13:45	Syracuse (Regional Transportation Center)
Greyhound + FlixBus	Bus Wi‑Fi Toilet Power outlets	16:15	Bus station	21h 30m	13:45	Syracuse (Regional Transportation Center)

Compare 2 ways to travel from Florence to Syracuse

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Syracuse. The journey takes about 20 hours 5 minutes and with fares starting at just CLP 83,923, it presents an excellent value for a comfortable ride.

3bus per day

20h 5mAverage duration

643 milesDistance

26kgCO₂ emissions

	Average price	Average duration	CO₂ emissions	Actions
Bus	Average priceCLP 83,923 - CLP 278,138	Average duration20h 5m	CO₂ emissions 26kg CO₂e
Train	Average priceCLP 231,785 - CLP 274,638	Average duration20h 19m	CO₂ emissions 94kg CO₂e

Bus stations and stops in Florence and Syracuse

Stops in Florence

A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA
Visit page
B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA

Stops in Syracuse

A
Regional Transportation Center
1 Walsh Circle Ste 30, Syracuse, NY 13208
B
Syracuse Airport
Visit page
C
Syracuse University
Bus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210
Visit page
D
Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA
E
New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA
F
Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA

Compare bus companies

Greyhound

3.5/588,177 reviews

Staff3.6

Timeliness3.0

Cleanliness3.4

Wi‑Fi2.5

Based on 88177 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi‑Fi. Greyhound ticket prices on this trip start at CLP 113,507

US bus companies:FlixBus, Greyhound, Futura, Tufesa, Chihuahuenses, Adirondack Trailways, Valley Transit

Frequently asked questions about travelling by bus from Florence, SC, US to Syracuse, US

Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.

How much is the bus ticket from Florence to Syracuse?
The cheapest coach tickets from Florence to Syracuse start from CLP 83,923. The average price for this route is around CLP 126,323. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Florence to Syracuse?
The average bus journey time from Florence to Syracuse is 20h 5m, covering a distance of 643 miles. The fastest bus can take you there in 22h 25m and is operated by Greyhound.
Which bus companies service the Florence to Syracuse route?
Several major bus companies operate on this route with 3 buses available per day.
What is the earliest and latest departure time for the bus from Florence to Syracuse?
The earliest bus departs from Florence to Syracuse at 00:05. And the latest bus departs at 19:20.
What are the CO₂ emissions for the bus trip from Florence to Syracuse?
A bus journey from Florence to Syracuse produces an estimated 25.8983 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.