Previously seen trips

Next departures for Florence to Syracuse on September 23
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location
FlixBus + Greyhound	Bus Wi‑Fi Toilet Power outlets	12:05am	Florence, SC	19h 25m	7:30pm	Syracuse (Regional Transportation Center)
Greyhound + FlixBus	Bus Wi‑Fi Toilet Power outlets	12:05am	Florence, SC	19h 25m	7:30pm	Syracuse (Regional Transportation Center)
FlixBus + Greyhound	Bus Wi‑Fi Toilet Power outlets	5:45am	Florence, SC	1d 9h	3:15pm	Syracuse (Regional Transportation Center)
FlixBus + Greyhound	Bus Wi‑Fi Toilet Power outlets	4:15pm	Bus station	21h 30m	1:45pm	Syracuse (Regional Transportation Center)
Greyhound + FlixBus	Bus Wi‑Fi Toilet Power outlets	4:15pm	Bus station	21h 30m	1:45pm	Syracuse (Regional Transportation Center)

Compare 2 ways to go from Florence to Syracuse

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Syracuse. The journey takes about 20 hours 5 minutes, and with fares starting at just $123, it presents an excellent value for a comfortable ride.

3bus per day

20h 5mAverage Duration

1036 kmDistance

26kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$123 - $407	Average Duration20h 5m	CO₂ emissions 26kg CO₂e
Train	Average Price$340 - $402	Average Duration20h 19m	CO₂ emissions 94kg CO₂e

Bus stations and stops in Florence and Syracuse

Stops in Florence

A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA
Visit page
B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA

Stops in Syracuse

A
Regional Transportation Center
1 Walsh Circle Ste 30, Syracuse, NY 13208
B
Syracuse Airport
Visit page
C
Syracuse University
Bus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210
Visit page
D
Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA
E
New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA
F
Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA

Compare bus companies

Greyhound

3.5/588,163 reviews

Staff3.6

Timeliness3.0

Cleanliness3.4

Wi‑Fi2.5

Based on 88163 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi‑Fi. Greyhound ticket prices on this trip start at $167

US bus companies:FlixBus, Greyhound, Futura, Tufesa, Chihuahuenses, Adirondack Trailways, Valley Transit

Frequently asked questions about travelling from Florence, SC, US to Syracuse, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Florence to Syracuse?
The cheapest bus tickets from Florence to Syracuse start from $123. The average price for this route is around $185. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Florence to Syracuse?
The average bus travel time from Florence to Syracuse is 20h 5m, covering a distance of 1036 km. The quickest bus can get you there in 22h 25m and is operated by Greyhound.
Which bus companies service the Florence to Syracuse route?
Several major bus companies operate on this route with 3 buses available per day.
What are the earliest and latest departure times for the bus from Florence to Syracuse?
The earliest bus departs from Florence to Syracuse at 12:05am. And the latest bus departs at 7:20pm.
What are the CO₂ emissions for the bus trip from Florence to Syracuse?
A bus trip from Florence to Syracuse generates an estimated 25.8983 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.