How much does a bus ticket from Boston to St. Louis cost?

The bus ticket price from Boston to St. Louis starts at US$123. The best way to find cheap bus tickets from Boston to St. Louis is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

How long is the bus ride from Boston to St. Louis?

The average travel time between Boston and St. Louis is around 1d 7h, although the fastest bus will take about 1d 4h. This is the time it takes to travel the 1669 km that separates the two cities.

How many daily bus connections are there between Boston and St. Louis?

The number of buses from Boston to St. Louis can differ depending on the day of the week. On average, there are 7 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Boston to St. Louis by comparing and selecting the bus that fits your travel style and budget on Busbud.

Which bus companies travel from Boston to St. Louis?

When taking the bus from Boston to St. Louis, you can travel comfortably and safely with Greyhound, FlixBus.

What are the departure and arrival stations when taking the bus from Boston to St. Louis?

Buses travelling between Boston and St. Louis leave from Back Bay Station or South Station and arrive at Gateway Station.

Bus Boston to St. Louis from US$110 | Refundable Tickets

Previously seen journeys

Next departures from Boston to St. Louis on 2 November
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	09:45	Boston (South Station)	1d 6h	15:10	Gateway Station	No tags
Greyhound + FlixBus	13:45	151 Steel Pl, Cambridge	1d 10h	23:15	Gateway Station	No tags
FlixBus + Greyhound	13:45	151 Steel Pl, Cambridge	1d 10h	23:15	Gateway Station	No tags
	08:30	Boston (South Station)	1d 7h	15:10	Gateway Station	No tags
FlixBus + Greyhound	13:45	151 Steel Pl, Cambridge	1d 10h	23:15	Gateway Station	No tags

Compare 2 ways to travel from Boston to St. Louis

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach St. Louis. The journey takes about 1 day, 7 hours 20 minutes and with fares starting at just US$123, it presents an excellent value for a comfortable ride.

7bus per day

1d 7hAverage duration

1668 kmDistance

42kgCO₂ emissions

	Average price	Average duration	CO₂ emissions
Bus	Average priceUS$123 - US$385	Average duration1d 7h	CO₂ emissions 42kg CO₂e
Train	Average priceUS$280 - US$1 677	Average duration1d 10h	CO₂ emissions 151kg CO₂e

Bus Boston, MA, US to St. Louis: Trip Overview

Average ticket priceUS$204

Average bus trip duration1d 7h

Number of daily buses7

Earliest bus departure01:30

Distance1667 km

Latest bus departure22:00

Compare bus companies

Greyhound

3.5/587 346 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

WiFi2.4

FlixBus

3.5/511 153 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

WiFi2.7

US Bus Companies: FlixBus, BlaBlaCar Bus, Greyhound, Sindbad, Infobus, Gontijo, Rider Express

Boston to St. Louis Bus

With Busbud, comparing and booking tickets for a bus from Boston to St. Louis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Boston to St. Louis.

Discover how much the bus trip from Boston to St. Louis will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Where are the popular stops in Boston and St. Louis?

Stops in Boston

A - Back Bay Station

B - South Station

C - North Station

D - Copley Square

E - Prudential MBTA Station

F - Copley MBTA Station

Stops in St. Louis

A - Gateway Station

Frequently asked questions on the trip Boston, MA, US - St. Louis

How much does a bus ticket from Boston to St. Louis cost?
The bus ticket price from Boston to St. Louis starts at US$123. The best way to find cheap bus tickets from Boston to St. Louis is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Boston to St. Louis?
The average travel time between Boston and St. Louis is around 1d 7h, although the fastest bus will take about 1d 4h. This is the time it takes to travel the 1669 km that separates the two cities.
How many daily bus connections are there between Boston and St. Louis?
The number of buses from Boston to St. Louis can differ depending on the day of the week. On average, there are 7 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Boston to St. Louis by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Boston to St. Louis?
When taking the bus from Boston to St. Louis, you can travel comfortably and safely with Greyhound, FlixBus.
What are the departure and arrival stations when taking the bus from Boston to St. Louis?
Buses travelling between Boston and St. Louis leave from Back Bay Station or South Station and arrive at Gateway Station.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

30/10

US$179

31/10

US$186

Today

US$231

02/11

US$240

03/11

No data

04/11

US$116

05/11

US$110

06/11

No data

The cheapest trip from Boston, MA, US to St. Louis was searched and found on 05 Nov 2025 with a price of US$110

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Boston, MA, US to St. Louis as early as possible.

You can expect to pay from US$110 to US$306 for a bus ticket from Boston, MA, US to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at US$110, which is on 2025-11-05.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Boston to St. Louis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Boston to St. Louis.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Boston to St. Louis will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Make a music playlist for your bus ride from Boston to St. Louis, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

What's the cheapest way to go from Boston, MA, US to St. Louis?

The bus is the cheapest travel choice for this destination

Vehicle type	Travel time	Avg price	Daily departures
Vehicle typeBus	Travel time1d 7h	Avg priceUS$204	Daily departures7
Vehicle typeTrain	Travel time1d 10h	Avg priceUS$555	Daily departures1

Will you be returning to Boston, MA, US by bus?

Bus from St. Louis to Boston, MA, US

You can also go to St. Louis by train

Train from Boston, MA, US to St. Louis

Top travelled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

Find coaches from Boston, MA, US to St. Louis