Bus Tickets from Boston, MA, US to St. Louis

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SatAug 30
from US$175
SunAug 31
from US$120
MonSep 1
TueSep 2
from US$114
WedSep 3
from US$114
ThuSep 4
from US$100
FriSep 5
SatSep 6

Cheap buses leaving Sunday

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: August 31 at
    Departure city: Boston
    Departure location: Boston (South Station)
    Arrival time: September 1 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: August 31 at
    Departure city: Boston
    Departure location: Boston (South Station)
    Arrival time: September 1 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 31 at
    Departure city: Boston
    Departure location: Boston (South Station)
    Arrival time: September 1 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 31 at
    Departure city: Boston
    Departure location: Boston (South Station)
    Arrival time: September 2 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 31 at
    Departure city: Boston
    Departure location: Boston (South Station)
    Arrival time: September 1 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Compare 2 ways to go from Boston to St. Louis

Bus
Average PriceUS$99 - US$308Average Duration1d 9h
42kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average PriceUS$351 - US$569Average Duration1d 10h
151kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Boston to St. Louis

Among the sustainable travel choices, the bus stands out as a good way to reach St. Louis. The journey takes about 1 day, 9 hours 25 minutes, and with fares starting at just US$99, it presents an excellent value for a comfortable ride.

6bus per day
1d 9hAverage Duration
US$99Cheapest ticket
42kgCO₂ emissions

Bus Boston, MA, US to St. Louis: Trip Overview

Average Ticket PriceUS$154
Average Bus Trip Duration1d 9h
Number of daily buses6
Earliest bus departure1:30am
Distance1676 km
Latest bus departure10:00pm

Boston to St. Louis Bus

With Busbud, comparing and booking tickets for a bus from Boston to St. Louis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Boston to St. Louis.

Discover how much the bus trip from Boston to St. Louis will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Boston, MA, US - St. Louis

  1. What is the distance between Boston and St. Louis?

    Boston and St. Louis are 1669 km (1035 miles) apart.

  2. What are the departure and arrival locations for buses traveling from Boston to St. Louis?

    Buses departing from Back Bay Station in Boston will take you to Gateway Station in St. Louis.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-26
No data
08-27
US$93
Today
US$143
08-29
US$165
08-30
US$194
08-31
US$112
09-01
No data
09-02
US$140
busbud logoThe cheapest trip from Boston, MA, US to St. Louis was searched and found on Aug 27, 2025 with a price of US$93

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Boston, MA, US to St. Louis, as early as possible.

You can expect to pay from US$93 to US$291 for a bus ticket from Boston, MA, US to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at US$112 which is on 2025-08-31.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Boston to St. Louis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Boston to St. Louis.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Boston to St. Louis will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Boston to St. Louis, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

What's the cheapest way to go from Boston, MA, US to St. Louis?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Boston, MA, US by bus?

Bus from St. Louis to Boston, MA, US

You can also go to St. Louis by train

Train from Boston, MA, US to St. Louis

Why choose Busbud?

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