Bus Tickets from Boston, MA, US to St. Louis

Next departures

Next departures for Boston to St. Louis on November 2
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
    		Brookline
    		Gateway StationCheapest
    Greyhound Lines, Inc.
      		Boston (South Station)
      		Gateway StationFastest
      Greyhound Lines, Inc.
        		Boston (South Station)
        		Gateway StationNo tags
        FlixBus + Greyhound Lines, Inc.
          		Boston (South Station)
          		Gateway StationNo tags
          Greyhound Lines, Inc.
            		Boston (South Station)
            		Gateway StationNo tags

            Last refresh of the prices: Yesterday at 4:21 PM EDT.

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            Compare 2 ways to go from Boston to St. Louis

            We recommend taking the bus

            Among the sustainable travel choices, the bus stands out as a good way to reach St. Louis. The journey takes about 1 day, 7 hours 20 minutes, and with fares starting at just US$123, it presents an excellent value for a comfortable ride.

            7bus per day
            1d 7hAverage Duration
            1668 kmDistance
            42kgCO₂ emissions
            Bus
            		Average PriceUS$123 - US$385Average Duration1d 7h
            42kg CO₂e
            Train
            		Average PriceUS$280 - US$1,677Average Duration1d 10h
            151kg CO₂e

            Bus Boston, MA, US to St. Louis: Trip Overview

            Average Ticket PriceUS$204
            Average Bus Trip Duration1d 7h
            Number of daily buses7
            Earliest bus departure1:30am
            Distance1667 km
            Latest bus departure10:00pm

            Boston to St. Louis Bus

            With Busbud, comparing and booking tickets for a bus from Boston to St. Louis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

            We make it our job to connect you with the most dependable bus companies that cover bus service from Boston to St. Louis.

            Discover how much the bus trip from Boston to St. Louis will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

            Frequently asked questions on the trip Boston, MA, US - St. Louis

            1. What is the distance between Boston and St. Louis?

              Boston and St. Louis are 1669 km (1035 miles) apart.

            2. What are the departure and arrival locations for buses traveling from Boston to St. Louis?

              Buses departing from Back Bay Station in Boston will take you to Gateway Station in St. Louis.

            Find cheapest prices for buses

            Price is for a one-way ticket for one passenger and based on past searches.

            Best price found
            10-30
            US$179
            10-31
            US$186
            Today
            US$231
            11-02
            US$240
            11-03
            No data
            11-04
            US$116
            11-05
            US$110
            11-06
            No data
            busbud logoThe cheapest trip from Boston, MA, US to St. Louis was searched and found on Nov 5, 2025 with a price of US$110

            To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Boston, MA, US to St. Louis, as early as possible.

            You can expect to pay from US$110 to US$306 for a bus ticket from Boston, MA, US to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at US$110 which is on 2025-11-05.

            About Bus Travel

            Bus Travel Tips

            Meet and talk to locals at the bus stations while travelling from Boston to St. Louis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

            From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Boston to St. Louis.

            Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Boston to St. Louis will emit less CO2 than a car or an airplane.

            Make a music playlist for your bus ride from Boston to St. Louis, and enjoy the scenery to tunes from your own personal soundtrack.

            Did you know?

            The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

            Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

            Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

            What's the cheapest way to go from Boston, MA, US to St. Louis?

            busbud logoThe bus is the cheapest travel choice for this destination

            Will you be returning to Boston, MA, US by bus?

            Bus from St. Louis to Boston, MA, US

            You can also go to St. Louis by train

            Train from Boston, MA, US to St. Louis

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