Find coaches from Buffalo, NY to Charleston, SC, US

Previously seen journeys

Next departures from Buffalo to Charleston on 31 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound + FlixBus
Buffalo (BUF) Airport
4565 Gaynor Ave, North CharlestonNo tags
Greyhound + FlixBus
Buffalo (BUF) Airport
4565 Gaynor Ave, North CharlestonNo tags
FlixBus + Greyhound
Niagara Frontier Transportation Authority
4565 Gaynor Ave, North CharlestonNo tags
FlixBus + Greyhound
Buffalo (BUF) Airport
4565 Gaynor Ave, North CharlestonNo tags
Greyhound + FlixBus
Buffalo (BUF) Airport
4565 Gaynor Ave, North CharlestonNo tags

Accepted payments

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Compare 2 ways to travel from Buffalo to Charleston

busbud logoWe recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach Charleston. The journey takes about 1 day, 13 minutes and with fares starting at just US$222, it presents an excellent value for a comfortable ride.

2train per day
1d Average duration
1117 kmDistance
102kgCO₂ emissions
Bus
Average priceUS$164 - US$252Average duration1d 5h
28kg CO₂e
Train
Average priceUS$222 - US$470Average duration1d
102kg CO₂e

Bus Buffalo, NY to Charleston, SC, US: Trip Overview

Average ticket priceUS$178
Average bus trip duration1d 5h
Number of daily buses3
Earliest bus departure07:30
Distance1124 km
Latest bus departure23:59

Buffalo to Charleston Bus

With Busbud, comparing and booking tickets for a bus from Buffalo to Charleston is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Buffalo to Charleston.

From cheap bus tickets to more luxurious buses travelling from Buffalo to Charleston, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Buffalo, NY - Charleston, SC, US

  1. How much does a bus ticket from Buffalo to Charleston cost?

    The bus ticket price from Buffalo to Charleston starts at US$164. The best way to find cheap bus tickets from Buffalo to Charleston is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Buffalo to Charleston?

    The average travel time between Buffalo and Charleston is around 1d 5h, although the fastest bus will take about 1d 4h. This is the time it takes to travel the 1129 km that separates the two cities.

  3. How many daily bus connections are there between Buffalo and Charleston?

    The number of buses from Buffalo to Charleston can differ depending on the day of the week. On average, there are 3 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Buffalo to Charleston by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from Buffalo to Charleston?

    When taking the bus from Buffalo to Charleston, you can travel comfortably and safely with FlixBus.

  5. What are the departure and arrival stations when taking the bus from Buffalo to Charleston?

    Buses travelling between Buffalo and Charleston leave from Buffalo Airport or Transportation Center and arrive at Charleston Bus Station.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
28/10
No data
29/10
US$180
Today
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31/10
No data
01/11
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02/11
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03/11
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04/11
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busbud logoThe cheapest trip from Buffalo, NY to Charleston, SC, US was searched and found on 29 Oct 2025 with a price of US$180

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Buffalo, NY to Charleston, SC, US as early as possible.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Buffalo to Charleston.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Buffalo to Charleston.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Buffalo to Charleston that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Buffalo to Charleston, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

What's the cheapest way to go from Buffalo, NY to Charleston, SC, US?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Buffalo, NY by bus?

Bus from Charleston, SC, US to Buffalo, NY

You can also go to Charleston, SC, US by train

Train from Buffalo, NY to Charleston, SC, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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