Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Niagara Frontier Transportation Authority | 4565 Gaynor Ave, North Charleston | Cheapest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Buffalo (BUF) Airport | 4565 Gaynor Ave, North Charleston | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Niagara Frontier Transportation Authority | 4565 Gaynor Ave, North Charleston | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Buffalo (BUF) Airport | 4565 Gaynor Ave, North Charleston | No tags |
Last refresh of the prices: Today at 7:14 PM EST.
Compare 2 ways to go from Buffalo to Charleston
Among the sustainable travel choices, the train stands out as the good way to reach Charleston. The journey takes about 1 day, 3 minutes and with fares starting at just $205, it presents an excellent value for a comfortable ride.
Where are the popular stops in Buffalo and Charleston?
Stops in Buffalo
- B185 Ellicott St, Buffalo, NY 14203, USA
- C75 Exchange St, Buffalo, NY 14203, USA
Stops in Charleston
- A
Charleston Bus Station
3610 Dorchester Rd, North Charleston, SC 29405
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Frequently asked questions about traveling from Buffalo, NY to Charleston, SC, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Buffalo to Charleston?
The cheapest bus tickets from Buffalo to Charleston start from $126. The average price for this route is around $174. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Buffalo to Charleston?
The average bus trip duration from Buffalo to Charleston is 1d 18h, covering a distance of 693 miles (1118 km). The quickest bus can get you there in 1d 10h and is operated by Greyhound.
Which bus companies service the Buffalo to Charleston route?
What is the earliest and latest departure time for the bus from Buffalo to Charleston?
The earliest bus departs from Buffalo to Charleston at 7:50am. And the latest bus departs at 11:59pm.
What are the CO₂ emissions for the bus trip from Buffalo to Charleston?
A bus trip from Buffalo to Charleston generates an estimated 28 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Buffalo to Charleston?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87463 reviews.
Which bus company has the best Wi-Fi from Buffalo to Charleston?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Buffalo to Charleston?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Buffalo to Charleston?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Buffalo, NY to Charleston, SC, US was searched and found on Jan 6, 2026 with a price of $118To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Buffalo, NY to Charleston, SC, US, as early as possible.
You can expect to pay from $118 to $132 for a bus ticket from Buffalo, NY to Charleston, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $118 which is on 2026-01-08.
What's the cheapest way to go from Buffalo, NY to Charleston, SC, US?
The Bus is the cheapest travel choice for this destination
