How much is the bus ticket from Buffalo to San Diego?

The cheapest bus tickets from Buffalo to San Diego start at R 3 854. The average price for this route is around R 6 546. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.

How long is the bus journey from Buffalo to San Diego?

The average bus journey time from Buffalo to San Diego is 3d 6h, covering a distance of 3528 km. The fastest bus gets you there in 3d 3h and is operated by Greyhound .

Which bus companies service the Buffalo to San Diego route?

Several major bus companies operate on this route with 16 buses available per day, including services from Greyhound , FlixBus .

What is the earliest and latest departure time for the bus from Buffalo to San Diego?

The earliest bus departs from Buffalo to San Diego at 07:55. And the latest bus departs at 23:20.

What are the CO₂ emissions for the bus trip from Buffalo to San Diego?

A bus trip from Buffalo to San Diego produces an estimated 88 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.

What is the best bus company from Buffalo to San Diego?

According to Busbud customers, the highest-rated bus company on this route is Greyhound , with an average rating of 3.5 out of 5 stars based on 87412 reviews.

Which bus company has the best Wi-Fi from Buffalo to San Diego?

Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company offers the most punctual service from Buffalo to San Diego?

According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Buffalo to San Diego?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Buffalo to San Diego from R 4 134 | Refundable Tickets

Previously seen journeys

Next departures from Buffalo to San Diego on 17 December
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound + FlixBus	Bus	17:20	Niagara Frontier Transportation Authority	3d 3h	17:35	UCSD Health La Jolla Station	No tags
FlixBus + Greyhound	Bus	17:20	Niagara Frontier Transportation Authority	3d 19h	10:10	Balboa Park	No tags
FlixBus + Greyhound	Bus	17:20	Niagara Frontier Transportation Authority	3d 7h	21:30	Downtown SD (Seaport)	No tags
FlixBus + Greyhound	Bus	17:20	Niagara Frontier Transportation Authority	3d 3h	18:10	San Diego (Old Town-FlixBus)	No tags
Greyhound + FlixBus	Bus	23:20	Buffalo (BUF) Airport	3d 4h	01:10	Downtown SD (Seaport)	No tags

Compare 2 ways to travel from Buffalo to San Diego

We recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach San Diego. The journey takes about 2 days, 15 hours 14 minutes and with fares starting at just R 6 018, it presents an excellent value for a comfortable ride.

2train per day

2d 15hAverage duration

3527 kmDistance

321kgCO₂ emissions

	Average price	Average duration	CO₂ emissions	Actions
Bus	Average priceR 3 854 - R 10 842	Average duration3d 6h	CO₂ emissions 88kg CO₂e
Train	Average priceR 6 018 - R 39 468	Average duration2d 15h	CO₂ emissions 321kg CO₂e

Where are the popular stops in Buffalo and San Diego?

Stops in Buffalo

A
Buffalo Airport
B
Transportation Center
185 Ellicott St, Buffalo, NY 14203, USA
Visit page
C
Exchange Street Station
75 Exchange St, Buffalo, NY 14203, USA
Visit page

Stops in San Diego

A
Mission Valley Sheraton
1433 Camino del Rio S, San Diego, CA 92108, USA
B
Old Town Courtyard Marriot
2435 Jefferson St, San Diego, CA 92110, USA
C
Downtown Holiday Inn
1617 1st Ave, San Diego, CA 92101, USA
D
Greyhound Station
1313 National Ave, San Diego, CA 92101, USA
E
Market St. & Park Blvd
601 Park Boulevard, San Diego, CA 92101, USA
F
San Ysidro McDonald's
727 E San Ysidro Blvd, San Diego, CA 92173, USA

Compare bus companies

Greyhound

3.5/587 438 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

WiFi2.4

FlixBus

3.5/511 635 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

WiFi2.7

US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Big Sky

Frequently asked questions about travelling from Buffalo, NY to San Diego, CA, US by bus

Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.

How much is the bus ticket from Buffalo to San Diego?
The cheapest bus tickets from Buffalo to San Diego start at R 3 854. The average price for this route is around R 6 546. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Buffalo to San Diego?
The average bus journey time from Buffalo to San Diego is 3d 6h, covering a distance of 3528 km. The fastest bus gets you there in 3d 3h and is operated by Greyhound.
Which bus companies service the Buffalo to San Diego route?
Several major bus companies operate on this route with 16 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from Buffalo to San Diego?
The earliest bus departs from Buffalo to San Diego at 07:55. And the latest bus departs at 23:20.
What are the CO₂ emissions for the bus trip from Buffalo to San Diego?
A bus trip from Buffalo to San Diego produces an estimated 88 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Buffalo to San Diego?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87412 reviews.
Which bus company has the best Wi-Fi from Buffalo to San Diego?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Buffalo to San Diego?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Buffalo to San Diego?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

15/12

No data

16/12

R 5 742

Today

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18/12

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19/12

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20/12

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The cheapest trip from Buffalo, NY to San Diego, CA, US was searched and found on 16 Dec 2025 with a price of R 5 742

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Buffalo, NY to San Diego, CA, US as early as possible.