Next bus departures

Next departures from Chicago to Durham on 18 April
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	13:30	Chicago 95Th & Dan Ryan	1d 2h	17:00	Durham	Cheapest
	Bus	14:45	Downtown Greyhound Station	1d	15:55	Durham	Fastest
	Bus	06:10	Downtown Greyhound Station	1d 1h	09:00	Durham	No tags
FlixBus + Greyhound Lines, Inc.	Bus	11:30	Downtown Greyhound Station	1d 2h	14:35	Durham	No tags
	Bus	18:00	Downtown Greyhound Station	1d 2h	21:10	Durham	No tags

Last refresh of the prices: Yesterday at 1:38 PM CDT.

Get from Chicago to Durham

This route is served by bus only

The journey takes about 1 day, 2 hours 30 minutes, and with fares starting at just ARS 129 945, it presents an excellent value for a comfortable ride.

14bus per day

1d 2hAverage duration

993 kmDistance

25kgCO₂ emissions

Where are the popular stops in Chicago and Durham?

Stops in Chicago

A
Downtown Greyhound Station
630 W Harrison St, Chicago, IL 60607, USA
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B
Chicago O'Hare International Airport
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C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA
D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA
E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA
F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA

Stops in Durham

A
Durham Greyhound Bus Station
515 W Pettigrew St , Durham, NC 27703
Visit page
B
Compare Foods Durham
2000-2004 NC-55, Durham, NC 27704, USA
C
Durham Compare Foods Durham
2000 Avondale Dr, Durham, NC 27704, USA
D
Durham, NC
E Main St at Roxboro St (WB), Durham, NC 27701, USA

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

15/04

ARS 142 263

16/04

ARS 135 288

Today

ARS 291 529

18/04

ARS 278 973

19/04

No data

20/04

No data

21/04

No data

22/04

ARS 153 423

The cheapest trip from Chicago to Durham, NC, US was searched and found on 16 Apr 2026 with a price of ARS 135 288

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Durham, NC, US as early as possible.

You can expect to pay from ARS 135 288 to ARS 342 432 for a bus ticket from Chicago to Durham, NC, US based on the last 2 days. You can expect to find the cheapest price for the trip at ARS 153 423, which is on 2026-04-22.