Next bus departures

Next departures from Chicago to Durham on 18 April
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	13:30	Chicago 95Th & Dan Ryan	1d 2h	17:00	Durham	Cheapest
	Bus	14:45	Downtown Greyhound Station	1d	15:55	Durham	Fastest
	Bus	06:10	Downtown Greyhound Station	1d 1h	09:00	Durham	No tags
FlixBus + Greyhound Lines, Inc.	Bus	11:30	Downtown Greyhound Station	1d 2h	14:35	Durham	No tags
	Bus	18:00	Downtown Greyhound Station	1d 2h	21:10	Durham	No tags

Last refresh of the prices: Yesterday at 1:38 PM CDT.

Get from Chicago to Durham

This route is served by bus only

The journey takes about 1 day, 2 hours 30 minutes, and with fares starting at just MX$1 647, it presents an excellent value for a comfortable ride.

14bus per day

1d 2hAverage duration

993 kmDistance

25kgCO₂ emissions

Where are the popular stops in Chicago and Durham?

Stops in Chicago

A
Downtown Greyhound Station
630 W Harrison St, Chicago, IL 60607, USA
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B
Chicago O'Hare International Airport
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C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA
D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA
E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA
F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA

Stops in Durham

A
Durham Greyhound Bus Station
515 W Pettigrew St , Durham, NC 27703
Visit page
B
Compare Foods Durham
2000-2004 NC-55, Durham, NC 27704, USA
C
Durham Compare Foods Durham
2000 Avondale Dr, Durham, NC 27704, USA
D
Durham, NC
E Main St at Roxboro St (WB), Durham, NC 27701, USA

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

15/04

MX$1 803

16/04

MX$1 715

Today

MX$3 694

18/04

MX$3 535

19/04

No data

20/04

No data

21/04

No data

22/04

MX$1 944

The cheapest trip from Chicago to Durham, NC, US was searched and found on 16 Apr 2026 with a price of MX$1 715

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Durham, NC, US as early as possible.

You can expect to pay from MX$1 715 to MX$4 339 for a bus ticket from Chicago to Durham, NC, US based on the last 2 days. You can expect to find the cheapest price for the trip at MX$1 944, which is on 2026-04-22.