How much is the bus ticket from Chicago to Durham?

The cheapest bus tickets from Chicago to Durham start from $105. The average price for this route is around $173. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Chicago to Durham?

The average bus trip duration from Chicago to Durham is 1d 1h, covering a distance of 619 miles (999 km). The quickest bus can get you there in 1d and is operated by Greyhound .

Which bus companies service the Chicago to Durham route?

Several major bus companies operate on this route with 9 buses available per day, including services from Greyhound , FlixBus .

What is the earliest and latest departure time for the bus from Chicago to Durham?

The earliest bus departs from Chicago to Durham at 5:25am. And the latest bus departs at 11:59pm.

What are the CO₂ emissions for the bus trip from Chicago to Durham?

A bus trip from Chicago to Durham generates an estimated 25 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Chicago to Durham?

According to Busbud customers, the highest-rated bus company on this route is Greyhound , with an average rating of 3.5 out of 5 stars based on 87412 reviews.

Which bus company has the best Wi-Fi from Chicago to Durham?

Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company has the most timely service from Chicago to Durham?

According to Busbud traveller reviews, the most timely bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Chicago to Durham?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Chicago to Durham from $97 | Refundable Tickets

Next bus departures

Next departures for Chicago to Durham on December 14
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	11:40pm	Chicago 95Th & Dan Ryan	1d	1:05am	Durham Greyhound Bus Station	CheapestFastest
Greyhound Lines, Inc. + FlixBus	Bus	10:50pm	Downtown Greyhound Station	1d 2h	2:35am	Durham Greyhound Bus Station	No tags
	Bus	11:10pm	537-517 W. Jackson Blvd	1d	1:05am	Durham Greyhound Bus Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	11:50pm	Chicago 95Th & Dan Ryan	1d 8h	9:00am	Durham Greyhound Bus Station	No tags

Last refresh of the prices: 12/07/2025 CST.

Compare 2 ways to go from Chicago to Durham

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Durham. The journey takes about 1 day, 1 hour 50 minutes and with fares starting at just $105, it presents an excellent value for a comfortable ride.

9bus per day

1d 1hAverage Duration

619 milesDistance

25kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$105 - $450	Average Duration1d 1h	CO₂ emissions 25kg CO₂e
Train	Average Price$280 - $280	Average Duration1d 13h	CO₂ emissions 91kg CO₂e

Where are the popular stops in Chicago and Durham?

Stops in Chicago

A
Downtown Greyhound Station
630 W Harrison St, Chicago, IL 60607, USA
Visit page
B
Chicago O'Hare International Airport
Visit page
C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA
D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA
E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA
F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA

Stops in Durham

A
Durham Greyhound Bus Station
515 W Pettigrew St , Durham, NC 27703
Visit page
B
Compare Foods Durham
2000-2004 NC-55, Durham, NC 27704, USA
C
Durham Compare Foods Durham
2000 Avondale Dr, Durham, NC 27704, USA
D
Durham, NC
E Main St at Roxboro St (WB), Durham, NC 27701, USA

Compare bus companies

Greyhound

3.5/587,431 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/511,611 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Big Sky

Frequently asked questions about traveling from Chicago to Durham, NC, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Chicago to Durham?
The cheapest bus tickets from Chicago to Durham start from $105. The average price for this route is around $173. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Chicago to Durham?
The average bus trip duration from Chicago to Durham is 1d 1h, covering a distance of 619 miles (999 km). The quickest bus can get you there in 1d and is operated by Greyhound.
Which bus companies service the Chicago to Durham route?
Several major bus companies operate on this route with 9 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from Chicago to Durham?
The earliest bus departs from Chicago to Durham at 5:25am. And the latest bus departs at 11:59pm.
What are the CO₂ emissions for the bus trip from Chicago to Durham?
A bus trip from Chicago to Durham generates an estimated 25 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Chicago to Durham?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87412 reviews.
Which bus company has the best Wi-Fi from Chicago to Durham?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Chicago to Durham?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Chicago to Durham?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

12/12

$138

12/13

$185

Today

$123

12/15

No data

12/16

No data

12/17

$117

12/18

No data

12/19

$157

The cheapest trip from Chicago to Durham, NC, US was searched and found on Dec 17, 2025 with a price of $117

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Durham, NC, US, as early as possible.

You can expect to pay from $117 to $266 for a bus ticket from Chicago to Durham, NC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $117 which is on 2025-12-17.

Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.