Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Downtown Greyhound Station | Louisville, KY | Cheapest | |||||
 | Chicago 95Th & Dan Ryan | Louisville, KY | Fastest | |||||
 | Chicago (Union Station), IL | Louisville, KY | No tags | |||||
| Downtown Greyhound Station | Louisville, KY | No tags | |||||
| Downtown Greyhound Station | Louisville, KY | No tags |
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Get from Chicago to Louisville
This route is served by bus onlyThe journey takes about 6 hours 45 minutes, and with fares starting at just US$30, it presents an excellent value for a comfortable ride.
Bus Chicago to Louisville: Trip Overview
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Chicago to Louisville Bus
With Busbud, comparing and booking tickets for a bus from Chicago to Louisville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make sure you can find a bus service from Chicago to Louisville from the most reliable bus companies operating this trip.
From cheap bus tickets to more luxurious buses travelling from Chicago to Louisville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Chicago and Louisville?
Frequently asked questions on the trip Chicago - Louisville
How much does a bus ticket from Chicago to Louisville cost?
The bus ticket price from Chicago to Louisville starts at US$30. The best way to find cheap bus tickets from Chicago to Louisville is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Chicago to Louisville?
The average travel time between Chicago and Louisville is around 6h 45m, although the fastest bus will take about 5h 5m. This is the time it takes to travel the 432 km that separates the two cities.
How many daily bus connections are there between Chicago and Louisville?
The number of buses from Chicago to Louisville can differ depending on the day of the week. On average, there are 18 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Chicago to Louisville by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Chicago to Louisville?
When taking the bus from Chicago to Louisville, you can travel comfortably and safely with Greyhound, FlixBus, Amtrak.
What are the departure and arrival stations when taking the bus from Chicago to Louisville?
Buses travelling between Chicago and Louisville leave from Downtown Greyhound Station or Chicago O'Hare International Airport and arrive at Louisville Greyhound Bus Station.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Chicago to Louisville was searched and found on 04 Nov 2025 with a price of US$25To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Louisville as early as possible.
You can expect to pay from US$25 to US$142 for a bus ticket from Chicago to Louisville based on the last 2 days. You can expect to find the cheapest price for the trip at US$25, which is on 2025-11-04.
Usually Amtrak, FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while travelling from Chicago to Louisville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Chicago to Louisville, get comfy and count the stars.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Chicago to Louisville that are otherwise impossible to come by with a plane.
Tune out to the fine sounds of your best music playlist on your bus trip from Chicago to Louisville while indulging in miles on end of beautiful scenic views.
Did you know?
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
Top travelled bus routes
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Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.
People from around the world trust Busbud
Popular Buses Connecting Chicago
Buses Leaving from Chicago
- Bus from Chicago to Columbia
- Coach Chicago - Toronto
- Bus Chicago - Seattle
- Bus from Chicago to Orlando
- Coach Chicago - Mexico City
- Bus Chicago - Washington
- Bus from Chicago to Iowa City
- Coach Chicago - Wildwood
- Bus Chicago - Centralia
- Bus from Chicago to Lewiston
- Coach Chicago - Mount Pleasant
- Bus Chicago - Kingman
- Bus from Chicago to Elkton
- Coach Chicago - Opelousas
- Bus Chicago - Brownsville
Buses Going to Chicago
- Bus from Boston to Chicago
- Coach Toronto - Chicago
- Bus Atlanta - Chicago
- Bus from Indianapolis to Chicago
- Coach Bridgeport - Chicago
- Bus Hamilton - Chicago
- Bus from Springfield to Chicago
- Coach Nashville - Chicago
- Bus Long Beach - Chicago
- Bus from Hickory to Chicago
- Coach Amsterdam - Chicago
- Bus Albion - Chicago
- Bus from Kerrville to Chicago
- Coach Boca Raton - Chicago
- Bus Lexington - Chicago
Popular Buses Connecting Louisville
Buses Leaving from Louisville
- Bus from Louisville to Chicago
- Coach Louisville - Indianapolis
- Bus Louisville - Atlanta
- Bus from Louisville to Portland
- Coach Louisville - Portland
- Bus Louisville - Las Vegas
- Bus from Louisville to Springfield
- Coach Louisville - Wilmington
- Bus Louisville - Cave City
- Bus from Louisville to Williamsburg
- Coach Louisville - Katy
- Bus Louisville - Wildwood
- Bus from Louisville to Bakersfield
- Coach Louisville - Eagle Pass
- Bus Louisville - Anniston
Buses Going to Louisville
- Bus from Cincinnati to Louisville
- Coach Nashville - Louisville
- Bus Chicago - Louisville
- Bus from Pittsburgh to Louisville
- Coach Portland - Louisville
- Bus Dallas - Louisville
- Bus from Daytona Beach to Louisville
- Coach Port Saint Lucie - Louisville
- Bus Brunswick - Louisville
- Bus from Ahoskie to Louisville
- Coach Colfax - Louisville
- Bus Scranton - Louisville
- Bus from San Francisco to Louisville
- Coach Macon - Louisville
- Bus Modesto - Louisville
Popular routes in this country
- Bus from Buffalo to Niagara Falls
- Coach Houston - Brownsville
- Bus New York City - Fleischmanns
- Bus from Miami to Orlando
- Coach Newark - Norfolk
- Bus Milwaukee - Appleton
- Bus from New York City to Pittsburgh
- Coach Harrisonburg - Blacksburg
- Bus Alexandria - Charlottesville
- Bus from Norfolk to Newark
- Coach Hartford - New York City
- Bus Rancho Cucamonga - Los Angeles
- Bus from Brownsville to Houston